Diarylheptanoid 35d overcomes EGFR TKI resistance by inducing hsp70-mediated lysosomal degradation of EGFR in EGFR-mutant lung adenocarcinoma

Xuan Hong, Min Tsang Hsieh, Tzu Yu Tseng, Hui Yi Lin, Hung Chih Chang, Sir Theng Yau, Wei Chung Cheng, Baozhen Ke, Hsiao Hui Liao, Chih Ying Wu, An An Liu, Meei Maan Wu, Kuo Yen Huang, Pan Chyr Yang, Sheng Chu Kuo, Mien Chie Hung, Pei Chih Lee

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Pharmacology, Toxicology and Pharmaceutical Science

Biochemistry, Genetics and Molecular Biology