Diabetes is associated with drug-resistant tuberculosis in Eastern Taiwan

A. H. Hsu; J. J. Lee; C. Y. Chiang; Y. H. Li; L. K. Chen; C. B. Lin

doi:10.5588/ijtld.11.0670

Diabetes is associated with drug-resistant tuberculosis in Eastern Taiwan

A. H. Hsu, J. J. Lee, C. Y. Chiang, Y. H. Li, L. K. Chen, C. B. Lin

Research output: Contribution to journal › Article › peer-review

25 Citations (Scopus)

Abstract

We assessed the association between diabetes mellitus and drug-resistant tuberculosis (TB). Among new patients, diabetes was significantly associated with any resistance to isoniazid excluding multidrug-resistant TB (MDR-TB; adjusted OR [aOR] 1.88, 95%CI 1.07-3.31), but not with MDR-TB (aOR 0.95, 95%CI 0.34-2.68). Among previously treated patients, diabetes was also significantly associated with INH resistance (aOR 6.76, 95%CI 1.53-29.98) but not with MDR-TB (aOR 1.52, 95%CI 0.59-3.95). We concluded that diabetes was associated with INH resistance and speculated that the sample size of retreatment cases was insufficient to confirm the association between diabetes and MDR-TB.

Original language	English
Pages (from-to)	354-356
Number of pages	3
Journal	International Journal of Tuberculosis and Lung Disease
Volume	17
Issue number	3
DOIs	https://doi.org/10.5588/ijtld.11.0670
Publication status	Published - Mar 1 2013

Keywords

Diabetes
Isoniazid resistance
Multidrug-resistant tuberculosis
Transmission

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.5588/ijtld.11.0670

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abstract = "We assessed the association between diabetes mellitus and drug-resistant tuberculosis (TB). Among new patients, diabetes was significantly associated with any resistance to isoniazid excluding multidrug-resistant TB (MDR-TB; adjusted OR [aOR] 1.88, 95%CI 1.07-3.31), but not with MDR-TB (aOR 0.95, 95%CI 0.34-2.68). Among previously treated patients, diabetes was also significantly associated with INH resistance (aOR 6.76, 95%CI 1.53-29.98) but not with MDR-TB (aOR 1.52, 95%CI 0.59-3.95). We concluded that diabetes was associated with INH resistance and speculated that the sample size of retreatment cases was insufficient to confirm the association between diabetes and MDR-TB.",

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T1 - Diabetes is associated with drug-resistant tuberculosis in Eastern Taiwan

AU - Hsu, A. H.

AU - Lee, J. J.

AU - Chiang, C. Y.

AU - Li, Y. H.

AU - Chen, L. K.

AU - Lin, C. B.

PY - 2013/3/1

Y1 - 2013/3/1

N2 - We assessed the association between diabetes mellitus and drug-resistant tuberculosis (TB). Among new patients, diabetes was significantly associated with any resistance to isoniazid excluding multidrug-resistant TB (MDR-TB; adjusted OR [aOR] 1.88, 95%CI 1.07-3.31), but not with MDR-TB (aOR 0.95, 95%CI 0.34-2.68). Among previously treated patients, diabetes was also significantly associated with INH resistance (aOR 6.76, 95%CI 1.53-29.98) but not with MDR-TB (aOR 1.52, 95%CI 0.59-3.95). We concluded that diabetes was associated with INH resistance and speculated that the sample size of retreatment cases was insufficient to confirm the association between diabetes and MDR-TB.

AB - We assessed the association between diabetes mellitus and drug-resistant tuberculosis (TB). Among new patients, diabetes was significantly associated with any resistance to isoniazid excluding multidrug-resistant TB (MDR-TB; adjusted OR [aOR] 1.88, 95%CI 1.07-3.31), but not with MDR-TB (aOR 0.95, 95%CI 0.34-2.68). Among previously treated patients, diabetes was also significantly associated with INH resistance (aOR 6.76, 95%CI 1.53-29.98) but not with MDR-TB (aOR 1.52, 95%CI 0.59-3.95). We concluded that diabetes was associated with INH resistance and speculated that the sample size of retreatment cases was insufficient to confirm the association between diabetes and MDR-TB.

KW - Diabetes

KW - Isoniazid resistance

KW - Multidrug-resistant tuberculosis

KW - Transmission

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Diabetes is associated with drug-resistant tuberculosis in Eastern Taiwan

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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