Development and biocompatibility tests of electrospun poly-l-lactide nanofibrous membranes incorporating oleic acid-coated Fe3O 4

Hsin Ta Wang; Ya Hui Chan; Sheng-Wei Feng; Yi June Lo; Nai Chia Teng; Haw Ming Huang

doi:10.1515/polyeng-2013-0206

Development and biocompatibility tests of electrospun poly-l-lactide nanofibrous membranes incorporating oleic acid-coated Fe3O 4

Hsin Ta Wang, Ya Hui Chan, Sheng-Wei Feng, Yi June Lo, Nai Chia Teng, Haw Ming Huang

Research output: Contribution to journal › Article › peer-review

13 Citations (Scopus)

Abstract

The aim of this study was to develop an electrospun poly-l-lactide (PLLA) nanofibrous membrane incorporating oleic acid-coated Fe₃O ₄. The Fe₃O₄ nanoparticles were prepared using the chemical co-precipitation method, and particle diameters were analyzed using transmission electron microscopy. After mixing the oleic acid-coated Fe ₃O₄ nanoparticles and PLLA, a membrane with nanofibers was manufactured using the electrospinning technique. Our results showed that Fe₃O₄ nanoparticle diameters fabricated in this study were concentrated at 2-8 nm (84.2%). After magnetizing, there exists an approximately linear relationship between magnetic flux density and membrane thickness (R²=0.7, p3O₄/PLLA nanomembranes exhibited a more spreading and attached phenotype. These results can serve as a reference for future advanced studies.

Original language	English
Pages (from-to)	241-245
Number of pages	5
Journal	Journal of Polymer Engineering
Volume	34
Issue number	3
DOIs	https://doi.org/10.1515/polyeng-2013-0206
Publication status	Published - May 1 2014

Keywords

electrospinning
magnetite
nanofibrous membrane
oleic acid
poly-l-lactide

ASJC Scopus subject areas

General Chemical Engineering
Materials Chemistry
Polymers and Plastics

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title = "Development and biocompatibility tests of electrospun poly-l-lactide nanofibrous membranes incorporating oleic acid-coated Fe3O 4",

abstract = "The aim of this study was to develop an electrospun poly-l-lactide (PLLA) nanofibrous membrane incorporating oleic acid-coated Fe3O 4. The Fe3O4 nanoparticles were prepared using the chemical co-precipitation method, and particle diameters were analyzed using transmission electron microscopy. After mixing the oleic acid-coated Fe 3O4 nanoparticles and PLLA, a membrane with nanofibers was manufactured using the electrospinning technique. Our results showed that Fe3O4 nanoparticle diameters fabricated in this study were concentrated at 2-8 nm (84.2%). After magnetizing, there exists an approximately linear relationship between magnetic flux density and membrane thickness (R2=0.7, p3O4/PLLA nanomembranes exhibited a more spreading and attached phenotype. These results can serve as a reference for future advanced studies.",

keywords = "electrospinning, magnetite, nanofibrous membrane, oleic acid, poly-l-lactide",

author = "Wang, {Hsin Ta} and Chan, {Ya Hui} and Sheng-Wei Feng and Lo, {Yi June} and Teng, {Nai Chia} and Huang, {Haw Ming}",

year = "2014",

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doi = "10.1515/polyeng-2013-0206",

language = "English",

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journal = "Journal of Polymer Engineering",

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T1 - Development and biocompatibility tests of electrospun poly-l-lactide nanofibrous membranes incorporating oleic acid-coated Fe3O 4

AU - Wang, Hsin Ta

AU - Chan, Ya Hui

AU - Feng, Sheng-Wei

AU - Lo, Yi June

AU - Teng, Nai Chia

AU - Huang, Haw Ming

PY - 2014/5/1

Y1 - 2014/5/1

N2 - The aim of this study was to develop an electrospun poly-l-lactide (PLLA) nanofibrous membrane incorporating oleic acid-coated Fe3O 4. The Fe3O4 nanoparticles were prepared using the chemical co-precipitation method, and particle diameters were analyzed using transmission electron microscopy. After mixing the oleic acid-coated Fe 3O4 nanoparticles and PLLA, a membrane with nanofibers was manufactured using the electrospinning technique. Our results showed that Fe3O4 nanoparticle diameters fabricated in this study were concentrated at 2-8 nm (84.2%). After magnetizing, there exists an approximately linear relationship between magnetic flux density and membrane thickness (R2=0.7, p3O4/PLLA nanomembranes exhibited a more spreading and attached phenotype. These results can serve as a reference for future advanced studies.

AB - The aim of this study was to develop an electrospun poly-l-lactide (PLLA) nanofibrous membrane incorporating oleic acid-coated Fe3O 4. The Fe3O4 nanoparticles were prepared using the chemical co-precipitation method, and particle diameters were analyzed using transmission electron microscopy. After mixing the oleic acid-coated Fe 3O4 nanoparticles and PLLA, a membrane with nanofibers was manufactured using the electrospinning technique. Our results showed that Fe3O4 nanoparticle diameters fabricated in this study were concentrated at 2-8 nm (84.2%). After magnetizing, there exists an approximately linear relationship between magnetic flux density and membrane thickness (R2=0.7, p3O4/PLLA nanomembranes exhibited a more spreading and attached phenotype. These results can serve as a reference for future advanced studies.

KW - electrospinning

KW - magnetite

KW - nanofibrous membrane

KW - oleic acid

KW - poly-l-lactide

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Development and biocompatibility tests of electrospun poly-l-lactide nanofibrous membranes incorporating oleic acid-coated Fe3O 4

Abstract

Keywords

ASJC Scopus subject areas

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