Abstract
Background: Creatinine secretion, as quantified by the ratio of creatinine clearance (CrCl) to glomerular filtration rate (GFR), may introduce another source of error when using serum creatinine concentration to estimate GFR. Few studies have examined determinants of the CrCl/GFR ratio. We sought to study whether higher levels of albuminuria would be associated with higher, and being non-Hispanic black with lower, CrCl/GFR ratio. Methods. We did a cross-sectional analysis of 1342 patients with chronic kidney disease from the Chronic Renal Insufficiency Cohort (CRIC) who had baseline measure of iothalamate GFR (iGFR) and 24-hour urine collections. Our predictors included urine albumin as determined from 24-hour urine collections (categorized as:
Original language | English |
---|---|
Article number | 268 |
Journal | BMC Nephrology |
Volume | 14 |
Issue number | 1 |
DOIs | |
Publication status | Published - Dec 5 2013 |
Keywords
- Albuminuria
- Chronic kidney disease
- Glomerular filtration rate
- Race/Ethnicity
ASJC Scopus subject areas
- Nephrology