Depression and anxiety in the early postpartum period: A comparative study among parents of full-term and preterm infants in Vietnam

Cai Thi Thuy Nguyen, Trung Quang Truong, Anh Thi Lan Nguyen, Huong Thi Vu, Lien Thi Kim Nguyen, Tri Manh Nguyen, Shu Yu Kuo

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Postpartum depression and anxiety impact both parental well-being and child health, with preterm infants being especially vulnerable. However, the link between maternal and paternal mental health remains underexplored. Aim: To examine depression and anxiety in mothers and fathers of full-term and preterm infants. Methods: A cross-sectional study was conducted on 336 mother-father-infant triads at a public hospital in Vietnam from December 2022 to April 2023. Parents of infants born before or after 37 weeks' gestation were recruited. The Edinburgh Postnatal Depression Scale and Zung's Self-Rated Anxiety Scale were used. Multilevel linear mixed-effects models were adopted. Findings: Among mothers, 42.4 % reported depressive symptoms compared to 29.4 % of fathers, and anxiety symptoms were also significantly prevalent in mothers (30.7 %) than in fathers (22.1 %) (p < 0.05). Moderate correlations were found between maternal and paternal symptoms (depression, r = 0.49; anxiety, r = 0.41). Parents of moderate or extremely/very preterm infants reported higher depression than those with late preterm or full-term infants, though anxiety differences were not significant. Being a mother (β = 1.09) and having an infant born at a lower gestational age (β = 0.69) were associated with greater depressive symptoms. In both parents, lower social support was associated with higher symptoms of depression (β = –1.38) and anxiety (β = –1.15). Conclusion: Mothers and fathers in Vietnam experienced substantial emotional distress. Early identification of depression and anxiety in parents of pre-term infants, particularly infants born earlier in gestation, is vital for maternity care professionals to promote family health.

Original languageEnglish
Article number104443
JournalMidwifery
Volume147
DOIs
Publication statusPublished - Aug 2025

Keywords

  • Anxiety
  • Depression
  • Parent
  • Postpartum
  • Preterm
  • Vietnam

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Maternity and Midwifery

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