Abstract
We report a 32-year-old male patient presented with acute deep vein thrombosis of his right leg after recent onset of active pulmonary tuberculosis. Marked hyperhomocysteinemia (> 50 μmol/L), folic acid deficiency, and abnormal coagulation profiles (elevations of fibrinogen and fibrinogen degradation product) were noted after a series of work-ups. After treatment with low-molecular-weight heparin, deep vein thrombosis improved. Serum homocysteine level returned to normal after folic acid and vitamin B12 supplementation for 2 months. After therapy with four-combined anti-tuberculosis drugs for 9 months, the pulmonary tuberculosis subsided. In the present case report, the cause of hyperhomocysteinemia may be related to folic acid deficiency and chronic renal insufficiency.
Original language | English |
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Pages (from-to) | 186-191 |
Number of pages | 6 |
Journal | Acta Cardiologica Sinica |
Volume | 23 |
Issue number | 3 |
Publication status | Published - Sept 2007 |
Keywords
- Deep vein thrombosis
- Folic acid deficiency
- Hypercoagulable state
- Hyperhomocysteinemia
- Pulmonary tuberculosis
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine