Data supporting the angiotensin II activates MEL18 to deSUMOylate HSF2 for hypertension-related heart failure

Chih Yang Huang; Chia Hua Kuo; Pei Ying Pai; Tsung Jung Ho; Yueh Min Lin; Ray Jade Chen; Fuu Jen Tsai; V. Vijaya Padma; Wei Wen Kuo; Chih Yang Huang

doi:10.1016/j.dib.2017.11.040

Data supporting the angiotensin II activates MEL18 to deSUMOylate HSF2 for hypertension-related heart failure

Chih Yang Huang, Chia Hua Kuo, Pei Ying Pai, Tsung Jung Ho, Yueh Min Lin, Ray Jade Chen, Fuu Jen Tsai, V. Vijaya Padma, Wei Wen Kuo, Chih Yang Huang

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

In association with the published article “Inhibition of HSF2 SUMOylation via MEL18 upregulates IGF-IIR and leads to hypertension-induced cardiac hypertrophy” (Huang et al., 2017) [1], this data article contains information about deSUMOylation of HSF2 on lysine 82 on angiotensin II (ANG II) -induced cardiac hypertrophy, which is mediated by MEL18. Isolated adult human whole heart tissue showed MEL18-mediated HSF2-IGF-IIR pathway is upregulated in hypertension human heart, compared to health human heart.

Original language	English
Pages (from-to)	521-526
Number of pages	6
Journal	Data in Brief
Volume	16
DOIs	https://doi.org/10.1016/j.dib.2017.11.040
Publication status	Published - Feb 1 2018

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.dib.2017.11.040

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title = "Data supporting the angiotensin II activates MEL18 to deSUMOylate HSF2 for hypertension-related heart failure",

abstract = "In association with the published article “Inhibition of HSF2 SUMOylation via MEL18 upregulates IGF-IIR and leads to hypertension-induced cardiac hypertrophy” (Huang et al., 2017) [1], this data article contains information about deSUMOylation of HSF2 on lysine 82 on angiotensin II (ANG II) -induced cardiac hypertrophy, which is mediated by MEL18. Isolated adult human whole heart tissue showed MEL18-mediated HSF2-IGF-IIR pathway is upregulated in hypertension human heart, compared to health human heart.",

author = "Huang, {Chih Yang} and Kuo, {Chia Hua} and Pai, {Pei Ying} and Ho, {Tsung Jung} and Lin, {Yueh Min} and Chen, {Ray Jade} and Tsai, {Fuu Jen} and {Vijaya Padma}, V. and Kuo, {Wei Wen} and Huang, {Chih Yang}",

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doi = "10.1016/j.dib.2017.11.040",

language = "English",

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T1 - Data supporting the angiotensin II activates MEL18 to deSUMOylate HSF2 for hypertension-related heart failure

AU - Huang, Chih Yang

AU - Kuo, Chia Hua

AU - Pai, Pei Ying

AU - Ho, Tsung Jung

AU - Lin, Yueh Min

AU - Chen, Ray Jade

AU - Tsai, Fuu Jen

AU - Vijaya Padma, V.

AU - Kuo, Wei Wen

AU - Huang, Chih Yang

PY - 2018/2/1

Y1 - 2018/2/1

N2 - In association with the published article “Inhibition of HSF2 SUMOylation via MEL18 upregulates IGF-IIR and leads to hypertension-induced cardiac hypertrophy” (Huang et al., 2017) [1], this data article contains information about deSUMOylation of HSF2 on lysine 82 on angiotensin II (ANG II) -induced cardiac hypertrophy, which is mediated by MEL18. Isolated adult human whole heart tissue showed MEL18-mediated HSF2-IGF-IIR pathway is upregulated in hypertension human heart, compared to health human heart.

AB - In association with the published article “Inhibition of HSF2 SUMOylation via MEL18 upregulates IGF-IIR and leads to hypertension-induced cardiac hypertrophy” (Huang et al., 2017) [1], this data article contains information about deSUMOylation of HSF2 on lysine 82 on angiotensin II (ANG II) -induced cardiac hypertrophy, which is mediated by MEL18. Isolated adult human whole heart tissue showed MEL18-mediated HSF2-IGF-IIR pathway is upregulated in hypertension human heart, compared to health human heart.

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Data supporting the angiotensin II activates MEL18 to deSUMOylate HSF2 for hypertension-related heart failure

Abstract

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