Cytogenetic study of spontaneous abortions with the Giemsa banding method.

Among 102 spontaneous abortuses karyotyped, 29 were from parents with a history of unexplained recurrent spontaneous abortion (group A), and 73 were from parents without a history of recurrent spontaneous abortion (group B). The mean maternal ages of these two groups were not significantly different. The chromosomal aberration rate in group A was 48.3% and in group B was 53.4%. The difference was not significant. The most common chromosomal anomaly was autosomal trisomies in both groups, while monosomy X was more common in group B. The subsequent spontaneous abortion rate was also not significantly different between the two groups.