Curcumin functions as a MEK inhibitor to induce a synthetic lethal effect on KRAS mutant colorectal cancer cells receiving targeted drug regorafenib

Chi Shiuan Wu, Shan Ying Wu, Hsin Chih Chen, Chien An Chu, Han Hsuan Tang, Hsiao Sheng Liu, Yi Ren Hong, Chi Ying F. Huang, Guan Cheng Huang, Chun Li Su

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Biochemistry, Genetics and Molecular Biology

Pharmacology, Toxicology and Pharmaceutical Science