Cryptococcus neoformans peritonitis in two patients with liver cirrhosis

Shio Shin Jean, Jiun Ling Wang, Jann Tay Wang, Chi Tai Fang, Yee Chun Chen, Shan Chwen Chang

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)


Cryptococcus neoformans is an important pathogen in immunocompromised patients. We report 2 cases of spontaneous C. neoformans peritonitis in patients with liver cirrhosis, a condition not previously reported in Taiwan. Patient 1, a 59-year-old man with alcoholic liver cirrhosis, had primary C. neoformans peritonitis with fungemia. The patient recovered completely after prolonged fluconazole therapy without relapse. Patient 2, a 51-year-old woman with liver cirrhosis due to Budd-Chiari syndrome, had C. neoformans isolated from ascites, cerebrospinal fluid, and blood culture. In spite of adequate antifungal treatment, the patient died of fulminant sepsis. Information about the interaction and relation between liver cirrhosis and cryptococcal peritonitis is rare in the literature. The experience of these cases may help facilitate the diagnosis and treatment of cryptococcal peritonitis.

Original languageEnglish
Pages (from-to)39-42
Number of pages4
JournalJournal of the Formosan Medical Association
Issue number1
Publication statusPublished - 2005
Externally publishedYes


  • Cryptococcosis
  • Cryptococcus neoformans
  • Liver cirrhosis
  • Peritonitis

ASJC Scopus subject areas

  • General Medicine


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