The purpose of this study was to investigate the correlations of serum lipids, uric acid, and albumin, among mothers (n = 111), offspring (n = 208), and siblings (n = 57) in Taipei, Taiwan. Analytical items included serum triglyceride, serum total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, uric acid, and albumin. Statistical analysis was performed according to the SAS UNIVARIATE procedure; while regression coefficient, parent-offspring regressions, paired-comparison and heritability were estimated. These results show higher heritabilities of four types of serum lipids, uric acid and albumin between mothers and testers (b(YX)) or siblings (b(ZX)) by parent-offspring regression analysis. Regression coefficients (b(YX)) of six characters were significantly different (p <0.05 - 0.01). Regression coefficients (b(ZX)) for total cholesterol, low-density lipoprotein cholesterol, uric acid, and albumin were significantly different (p <0.05 - 0.01), showing the result of genetic control, because their heritabilities were very high at 0.75 ~ 1.0, 0.77 ~ 1.0, 0.96 ~ 1.0, and 0.48 ~ 0.82, respectively. This study disclosed that the serum lipids of children in Taipei, Taiwan were significantly correlated with that of parents, which may be attributed to the result of genetic control.
|Number of pages||8|
|Journal||Acta Paediatrica Taiwanica|
|Publication status||Published - Jul 1999|
- Serum lipids
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health