Corpus callosotomy in a patient of hemimegalencephaly and Lennox-Gastaut syndrome

Shang Yeong Kwan, Hann Yeh Shyu, Ji Ho Lin, Tai-Tong Wong, Kai Ping Chang, Chun Hing Yiu

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


We report the case of a girl with hemimegalencephaly (HME) and Lennox-Gastaut syndrome (LGS) treated by callosotomy at 1 year of age. Over 10 years, her seizure frequency and severity decreased markedly. Hemispherectomy is the main surgical option for HME although HME appears to correlate with a less favorable seizure outcome. However, the clinical presentation of LGS and possible generalized cortical dysplasia, which is indicative of a secondarily generalized epilepsy, might predict a favorable surgical outcome of corpus callosotomy in patients of HME, as in our case.

Original languageEnglish
Pages (from-to)643-646
Number of pages4
JournalBrain and Development
Issue number10
Publication statusPublished - Nov 1 2008
Externally publishedYes


  • Corpus callosotomy
  • Epilepsy
  • Generalized cortical dysplasia
  • Hemimegalencephaly
  • Lennox-Gastaut syndrome

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Developmental Neuroscience
  • Clinical Neurology


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