Contribution of ischemic stroke to hip fracture risk and the influence of gender difference

Chien Hua Wu, Tsan Hon Liou, Po Lung Hsiao, Yu Ching Lin, Kwang Hwa Chang

Research output: Contribution to journalArticlepeer-review

21 Citations (Scopus)


Objectives: To clarify the contribution of stroke to the risk of hip fracture (HF) and the influence of gender difference on HF, and to estimate the incidence rate of poststroke HF. Design: A prospective, probability-sampling, 10-year, population-based cohort study. Setting: A National Health Insurance Research Database consisting of 200,432 randomly selected enrollees. Participants: Subjects with acute ischemic stroke (N=1951; mean age ± SD, 65.6±9.8y; 56.5% men) were identified. For each stroke subject, 2 age- and gender-matched controls were recruited. Control subjects did not have any brain disease. Those subjects younger than 45 years were excluded. Interventions: Not applicable. Main Outcome Measures: The incidence rate and the adjusted hazard ratio of sustaining an HF were estimated. The cumulative HF-free probability was plotted. Results: Stroke subjects had a higher incidence rate of HF than their controls (women: 11.3 vs 4.4/1000 person-years, P

Original languageEnglish
Pages (from-to)1987-1991
Number of pages5
JournalArchives of Physical Medicine and Rehabilitation
Issue number12
Publication statusPublished - Dec 2011


  • Female
  • Femoral fractures
  • Hip
  • Rehabilitation
  • Risk
  • Stroke

ASJC Scopus subject areas

  • Rehabilitation
  • Physical Therapy, Sports Therapy and Rehabilitation


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