Continuous production of dicarboxylic acid by immobilized Pseudomonas aeruginosa cells

Err Cheng Chan; Chin Sheng Cheng; Yuan Hsun Hsu

doi:10.1016/S0922-338X(97)83575-1

Continuous production of dicarboxylic acid by immobilized Pseudomonas aeruginosa cells

Err Cheng Chan, Chin Sheng Cheng, Yuan Hsun Hsu

Graduate Institute of Medical Sciences

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

Treatment of Pseudomonas aeruginosa with 3% (v/v) Tween 80 resulted in a 16-fold increase in the yield of conversion of n-pentadecane to the corresponding dioic acid, tridecane 1,13-dicarboxylic acid (DC-15). However, this conversion process was inhibited by high concentrations of DC-15. To avoid this product inhibition, a continuous process with immobilized cells was performed, and the results showed that the DC-15 yield was four-fold higher than in the case of batch type DC-15 production. The continuous process used in this study is adaptable to large-scale production of DC-15.

Original language	English
Pages (from-to)	157-160
Number of pages	4
Journal	Journal of Fermentation and Bioengineering
Volume	83
Issue number	2
DOIs	https://doi.org/10.1016/S0922-338X(97)83575-1
Publication status	Published - 1997

Keywords

1,13-dicarboxylic acid
bioconversion
Pseudomonas aeruginosa

ASJC Scopus subject areas

Biotechnology
Applied Microbiology and Biotechnology

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10.1016/S0922-338X(97)83575-1

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title = "Continuous production of dicarboxylic acid by immobilized Pseudomonas aeruginosa cells",

abstract = "Treatment of Pseudomonas aeruginosa with 3% (v/v) Tween 80 resulted in a 16-fold increase in the yield of conversion of n-pentadecane to the corresponding dioic acid, tridecane 1,13-dicarboxylic acid (DC-15). However, this conversion process was inhibited by high concentrations of DC-15. To avoid this product inhibition, a continuous process with immobilized cells was performed, and the results showed that the DC-15 yield was four-fold higher than in the case of batch type DC-15 production. The continuous process used in this study is adaptable to large-scale production of DC-15.",

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AU - Chan, Err Cheng

AU - Cheng, Chin Sheng

AU - Hsu, Yuan Hsun

PY - 1997

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N2 - Treatment of Pseudomonas aeruginosa with 3% (v/v) Tween 80 resulted in a 16-fold increase in the yield of conversion of n-pentadecane to the corresponding dioic acid, tridecane 1,13-dicarboxylic acid (DC-15). However, this conversion process was inhibited by high concentrations of DC-15. To avoid this product inhibition, a continuous process with immobilized cells was performed, and the results showed that the DC-15 yield was four-fold higher than in the case of batch type DC-15 production. The continuous process used in this study is adaptable to large-scale production of DC-15.

AB - Treatment of Pseudomonas aeruginosa with 3% (v/v) Tween 80 resulted in a 16-fold increase in the yield of conversion of n-pentadecane to the corresponding dioic acid, tridecane 1,13-dicarboxylic acid (DC-15). However, this conversion process was inhibited by high concentrations of DC-15. To avoid this product inhibition, a continuous process with immobilized cells was performed, and the results showed that the DC-15 yield was four-fold higher than in the case of batch type DC-15 production. The continuous process used in this study is adaptable to large-scale production of DC-15.

KW - 1,13-dicarboxylic acid

KW - bioconversion

KW - Pseudomonas aeruginosa

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Continuous production of dicarboxylic acid by immobilized Pseudomonas aeruginosa cells

Abstract

Keywords

ASJC Scopus subject areas

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