Abstract
Biomoleculars act as a tool to build a multiple enzyme system based on human metabolic actions to perform basic logic operation connecting OR and AND gates. Three enzymes (invertase, amyloglucosidase, hexokinase) concert as a logic operation part, processing three molecular input signals (sucrose, maltose, and ATP) to produce G6P (glucose-6-phosphate). The other two enzymes glucose-6-phosphate dehydrogenase (G6PD) and salicylate hydroxylase (SHL) compose to function as a signal displayer. Furthermore, we used a latent fluorescent molecule composed of sacylate and fluorescence which can be catalyzed and release fluorescent molecular to produce output signal. According to our experiments, firstly, our design is proved. The typical characteristics of enzyme reactions have been discovered through comparing the expected theoretical cures with the result cures. Secondly, the possibility of applying multiple logic gates into complicate networks has been shown.
Original language | English |
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Title of host publication | Proceedings - 4th International Conference on Genetic and Evolutionary Computing, ICGEC 2010 |
Pages | 35-38 |
Number of pages | 4 |
DOIs | |
Publication status | Published - 2010 |
Event | 4th International Conference on Genetic and Evolutionary Computing, ICGEC 2010 - Shenzhen, China Duration: Dec 13 2010 → Dec 15 2010 |
Other
Other | 4th International Conference on Genetic and Evolutionary Computing, ICGEC 2010 |
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Country/Territory | China |
City | Shenzhen |
Period | 12/13/10 → 12/15/10 |
Keywords
- Bio-computing
- Boolean logic gates
- Enzymes
- Latent fluorophore
ASJC Scopus subject areas
- Computational Theory and Mathematics
- Theoretical Computer Science