Abstract
INTRODUCTION: Patients with portal vein thrombosis (PVT) may be asymptomatic but the consequences can be
severe. Early detection and treatment is crucial to avoid the severe consequences. Catheter-directed thrombolysis
(CDT) with anticoagulation played an important role in PVT in recent years. We present a case with concomitant
catheter-directed transhepatic thrombolysis and selective superior mesenteric artery infusion with urokinase and
heparin.
CASE REPORT: A 22-year-old woman had intermittent abdominal dull pain for 3 weeks. Computed tomography
revealed PVT. We performed concomitant catheter-directed transhepatic thrombolysis and selective superior
mesenteric artery infusion with urokinase and heparin. After 4-days thrombolysis treatment, the symptoms dissolved
and the follow-up ultrasound three months after discharge revealed patent portal vein without thrombosis.
DISCUSSION: Urokinase and heparin are widely used in thrombolysis of peripheral and central vascular thrombosis.
Thrombolysis for PVT can be performed via trans-arterial or transhepatic routes. Combination of these two methods
costs more time but offers ideal result. Awareness of the possible bleeding complication during infusion of the
thrombolytic agents is important.
severe. Early detection and treatment is crucial to avoid the severe consequences. Catheter-directed thrombolysis
(CDT) with anticoagulation played an important role in PVT in recent years. We present a case with concomitant
catheter-directed transhepatic thrombolysis and selective superior mesenteric artery infusion with urokinase and
heparin.
CASE REPORT: A 22-year-old woman had intermittent abdominal dull pain for 3 weeks. Computed tomography
revealed PVT. We performed concomitant catheter-directed transhepatic thrombolysis and selective superior
mesenteric artery infusion with urokinase and heparin. After 4-days thrombolysis treatment, the symptoms dissolved
and the follow-up ultrasound three months after discharge revealed patent portal vein without thrombosis.
DISCUSSION: Urokinase and heparin are widely used in thrombolysis of peripheral and central vascular thrombosis.
Thrombolysis for PVT can be performed via trans-arterial or transhepatic routes. Combination of these two methods
costs more time but offers ideal result. Awareness of the possible bleeding complication during infusion of the
thrombolytic agents is important.
| Translated title of the contribution | 伴隨導管定向溶栓治療肝膽和選擇性腸系膜上動脈灌注在一個年輕女子的近期門靜脈血栓形成 |
|---|---|
| Original language | English |
| Publication status | Published - Mar 2014 |
| Event | The 63rd Annual Meeting of RSROC - Chung Shan Medical University, Taichung, Taiwan Duration: Mar 22 2014 → Mar 23 2014 https://www.rsroc.org.tw/annual/annualnews_detail.asp?id=64 |
Conference
| Conference | The 63rd Annual Meeting of RSROC |
|---|---|
| Country/Territory | Taiwan |
| City | Taichung |
| Period | 3/22/14 → 3/23/14 |
| Internet address |