@article{3e82311302764f44af3bce8d329eeb52,
title = "Compassionate Treatment of Brainstem Tumors with Boron Neutron Capture Therapy: A Case Series",
abstract = "Brainstem tumors are heterogenous and cancerous glioma tumors arising from the midbrain, pons, and the medulla that are relatively common in children, accounting for 10% to 20% of all pediatric brain tumors. However, the prognosis of aggressive brainstem gliomas remains extremely poor despite aggressive treatment with chemotherapy and radiotherapy. That means there are many life-threatening patients who have exhausted all available treatment options and are beginning to face end-of-life stage. Therefore, the unique properties of highly selective heavy particle irradiation with.",
author = "Chen, {Yi Wei} and Lee, {Yi Yen} and Lin, {Chun Fu} and Huang, {Ting Yu} and Ke, {Shih Hung} and Mu, {Pei Fan} and Pan, {Po Shen} and Chen, {Jen Kun} and Lan, {Tien Li} and Hsu, {Ping Chuan} and Liang, {Muh Lii} and Chen, {Hsin Hung} and Chang, {Feng Chi} and Wu, {Chih Chun} and Lin, {Shih Chieh} and Lee, {Jia Cheng} and Chen, {Shih Kuan} and Liu, {Hong Ming} and Peir, {Jinn Jer} and Tsai, {Hui Yu} and Lin, {Ko Han} and Peng, {Nan Jing} and Chen, {Kuan Hsuan} and Wu, {Yuan Hung} and Kang, {Yu Mei} and Yang, {Wan Chin} and Liou, {Shueh Chun} and Huang, {Wei Hsuan} and Hiroki Tanaka and Wong, {Tai Tong} and Yee Chao and Chou, {Fong In}",
note = "Funding Information: First and foremost, I would like to acknowledge Professor Ming Lee and his colleagues at the College of Nuclear Science, National Tsing-Hua University for all the technique support. I would like to thank Chi-Wei Chang, a Nuclear Pharmacist from the Department of Nuclear Medicine, Taipei Veterans General Hospital for useful pharmaceutical comments. All authors also thank all colleagues from the Nuclear Science and Technology Development Center for providing a treatment plan system and the Taiwan Biotech Company for manufacturing high-quality L-BPA for this study. In addition, all authors are grateful to clinical research nurse Pei-Yu Lai and research assistants Meng-Hsuan Lin, Su-Chen Chung, Shu-Hua Shih and Chih-Lin Chao for providing high-quality nursing care after BNCT treatment. Besides, all authors would like to express highest gratitude for the colleagues, Chun-Mei Lin, Hsiao Wen Hsu, Hsin-Tzu Kao, Ching-Chia Chang, Chu-Chuan Hsieh, at International Medical Service Center of Taipei Veterans General Hospital. Finally, we would like to thank all members of the Research Center for Boron Neutron Capture Therapy at Tamkang University for their support in executing this study. Publisher Copyright: {\textcopyright} 2022 by the authors. Licensee MDPI, Basel, Switzerland.",
year = "2022",
month = apr,
doi = "10.3390/life12040566",
language = "English",
volume = "12",
journal = "Life",
issn = "0024-3019",
publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",
number = "4",
}
