Abstract
OBJECTIVE: To investigate the effects of flapless micro-osteoperforation and corticision on the rate of orthodontic tooth movement in rats.
MATERIALS AND METHODS: Forty-five 8-week-old male Sprague-Dawley rats were divided into the following groups: micro-osteoperforation and orthodontic force (MOP + F), corticision and orthodontic force (C + F), and orthodontic force only (F, control). The left maxillary first molars were pulled forward with a force of 50 g. Flapless surgical interventions were conducted in the MOP + F and C + F groups. The total duration of the experiment was 6 weeks. Alveolar bone density and the number of osteoclasts were evaluated using microcomputed tomography and histologic examination, respectively.
RESULTS: The tooth movement distance was significantly higher in both experimental groups than in the control group. Bone density and bone mineral density decreased in the MOP + F and C + F groups. The number of osteoclasts in the MOP + F and C + F groups was significantly higher than in the control group F.
CONCLUSION: The two minimally invasive flapless surgical interventions increased bone remodeling and osteoclast activity and induced faster orthodontic tooth movement for at least 2 weeks in rats. No differences were observed between the outcome of flapless micro-osteoperforation and corticision in the rats.
| Original language | English |
|---|---|
| Pages (from-to) | 558-64 |
| Number of pages | 7 |
| Journal | Angle Orthodontist |
| Volume | 86 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Jul 2016 |
Keywords
- Journal Article