Comorbidity profile of chronic rhinosinusitis: A population-based study

Shiu Dong Chung; Po Yueh Chen; Herng Ching Lin; Shih Han Hung

doi:10.1002/lary.24581

Comorbidity profile of chronic rhinosinusitis: A population-based study

Shiu Dong Chung, Po Yueh Chen, Herng Ching Lin, Shih Han Hung

Research output: Contribution to journal › Article › peer-review

55 Citations (Scopus)

Abstract

Objectives/Hypothesis This study aimed to explore the prevalence of a broad spectrum of comorbid medical conditions among patients with chronic rhinosinusitis (CRS), using a population-based dataset. Study design A cross-sectional study. Methods In total, 5,734 CRS subjects and 17,202 comparison subjects were included in this study. Separate conditional logistic regression analyses were performed to calculate the odds ratio (OR) for each of 39 medical comorbidities between subjects with and without CRS. Results For 27 of the 39 study comorbidities, results showed that subjects with CRS had a statistically significantly higher OR than subjects without CRS after adjusting for sociodemographic characteristics. Ranks of the top five comorbid relationships from the strongest ORs to the lowest were as follows: asthma (OR=3.09), chronic pulmonary disease (OR=3.04), weight loss (OR=2.58), obesity (OR=2.50), and migraines (OR=2.30). Conclusion Our results indicate that subjects with CRS have an increased prevalence of various comorbidities. Level of Evidence 3b. Laryngoscope, 124:1536-1541, 2014

Original language	English
Pages (from-to)	1536-1541
Number of pages	6
Journal	Laryngoscope
Volume	124
Issue number	7
DOIs	https://doi.org/10.1002/lary.24581
Publication status	Published - Jul 2014

Keywords

Chronic rhinosinusitis
comorbidity

ASJC Scopus subject areas

Otorhinolaryngology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1002/lary.24581

Cite this

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title = "Comorbidity profile of chronic rhinosinusitis: A population-based study",

abstract = "Objectives/Hypothesis This study aimed to explore the prevalence of a broad spectrum of comorbid medical conditions among patients with chronic rhinosinusitis (CRS), using a population-based dataset. Study design A cross-sectional study. Methods In total, 5,734 CRS subjects and 17,202 comparison subjects were included in this study. Separate conditional logistic regression analyses were performed to calculate the odds ratio (OR) for each of 39 medical comorbidities between subjects with and without CRS. Results For 27 of the 39 study comorbidities, results showed that subjects with CRS had a statistically significantly higher OR than subjects without CRS after adjusting for sociodemographic characteristics. Ranks of the top five comorbid relationships from the strongest ORs to the lowest were as follows: asthma (OR=3.09), chronic pulmonary disease (OR=3.04), weight loss (OR=2.58), obesity (OR=2.50), and migraines (OR=2.30). Conclusion Our results indicate that subjects with CRS have an increased prevalence of various comorbidities. Level of Evidence 3b. Laryngoscope, 124:1536-1541, 2014",

keywords = "Chronic rhinosinusitis, comorbidity",

author = "Chung, {Shiu Dong} and Chen, {Po Yueh} and Lin, {Herng Ching} and Hung, {Shih Han}",

year = "2014",

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doi = "10.1002/lary.24581",

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T1 - Comorbidity profile of chronic rhinosinusitis

T2 - A population-based study

AU - Chung, Shiu Dong

AU - Chen, Po Yueh

AU - Lin, Herng Ching

AU - Hung, Shih Han

PY - 2014/7

Y1 - 2014/7

N2 - Objectives/Hypothesis This study aimed to explore the prevalence of a broad spectrum of comorbid medical conditions among patients with chronic rhinosinusitis (CRS), using a population-based dataset. Study design A cross-sectional study. Methods In total, 5,734 CRS subjects and 17,202 comparison subjects were included in this study. Separate conditional logistic regression analyses were performed to calculate the odds ratio (OR) for each of 39 medical comorbidities between subjects with and without CRS. Results For 27 of the 39 study comorbidities, results showed that subjects with CRS had a statistically significantly higher OR than subjects without CRS after adjusting for sociodemographic characteristics. Ranks of the top five comorbid relationships from the strongest ORs to the lowest were as follows: asthma (OR=3.09), chronic pulmonary disease (OR=3.04), weight loss (OR=2.58), obesity (OR=2.50), and migraines (OR=2.30). Conclusion Our results indicate that subjects with CRS have an increased prevalence of various comorbidities. Level of Evidence 3b. Laryngoscope, 124:1536-1541, 2014

AB - Objectives/Hypothesis This study aimed to explore the prevalence of a broad spectrum of comorbid medical conditions among patients with chronic rhinosinusitis (CRS), using a population-based dataset. Study design A cross-sectional study. Methods In total, 5,734 CRS subjects and 17,202 comparison subjects were included in this study. Separate conditional logistic regression analyses were performed to calculate the odds ratio (OR) for each of 39 medical comorbidities between subjects with and without CRS. Results For 27 of the 39 study comorbidities, results showed that subjects with CRS had a statistically significantly higher OR than subjects without CRS after adjusting for sociodemographic characteristics. Ranks of the top five comorbid relationships from the strongest ORs to the lowest were as follows: asthma (OR=3.09), chronic pulmonary disease (OR=3.04), weight loss (OR=2.58), obesity (OR=2.50), and migraines (OR=2.30). Conclusion Our results indicate that subjects with CRS have an increased prevalence of various comorbidities. Level of Evidence 3b. Laryngoscope, 124:1536-1541, 2014

KW - Chronic rhinosinusitis

KW - comorbidity

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Comorbidity profile of chronic rhinosinusitis: A population-based study

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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