TY - JOUR
T1 - Comorbidity as an independent risk factor in patients with cancer
T2 - An 8-year population-based study
AU - Chen, Chang-I
AU - Kuan, Ching Feng
AU - Miser, James
AU - Fang, Yu Ann
AU - Lam, Carlos
AU - Chiu, Wen-Ta
AU - Li, Yu-Chuan
N1 - Publisher Copyright:
© 2013 APJPH.
PY - 2015/3/4
Y1 - 2015/3/4
N2 - This study determined the prevalence of medical conditions in patients with cancer and their impact on outcome. We evaluated a cohort of 37 411 patients diagnosed with cancer between 2000 and 2008 in Taiwan, collecting the cancer diagnosis and chronic disease diagnoses. The severity of the comorbid condition was correlated with the cancer diagnosis and outcome. Overall, 71.9% of the study population had 1 or more comorbid conditions. Patients with none (n = 10 508), 1 (n = 8881), 2 (n = 6583), and 3 or more (n = 11 439) comorbid conditions had mortality rates of 11.49%, 15.99%, 19.61%, and 29.39%, respectively. Older patients with comorbid conditions had a significantly higher chance of death. Dementia, heart disease, or cerebrovascular diseases were associated with the highest mortality. Cancer patients with comorbid conditions have a significantly higher risk of death. Prevention and better medical management of comorbid conditions is likely to result in improved outcomes for patients with cancer.
AB - This study determined the prevalence of medical conditions in patients with cancer and their impact on outcome. We evaluated a cohort of 37 411 patients diagnosed with cancer between 2000 and 2008 in Taiwan, collecting the cancer diagnosis and chronic disease diagnoses. The severity of the comorbid condition was correlated with the cancer diagnosis and outcome. Overall, 71.9% of the study population had 1 or more comorbid conditions. Patients with none (n = 10 508), 1 (n = 8881), 2 (n = 6583), and 3 or more (n = 11 439) comorbid conditions had mortality rates of 11.49%, 15.99%, 19.61%, and 29.39%, respectively. Older patients with comorbid conditions had a significantly higher chance of death. Dementia, heart disease, or cerebrovascular diseases were associated with the highest mortality. Cancer patients with comorbid conditions have a significantly higher risk of death. Prevention and better medical management of comorbid conditions is likely to result in improved outcomes for patients with cancer.
KW - cancer with comorbidity
KW - population study
KW - risk factor
UR - http://www.scopus.com/inward/record.url?scp=84926301504&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84926301504&partnerID=8YFLogxK
U2 - 10.1177/1010539513481491
DO - 10.1177/1010539513481491
M3 - Article
C2 - 23536238
AN - SCOPUS:84926301504
SN - 1010-5395
VL - 27
SP - NP590-NP599
JO - Asia-Pacific Journal of Public Health
JF - Asia-Pacific Journal of Public Health
IS - 2
ER -
