TY - GEN
T1 - Clinical Usefulness of Drug-Disease Interaction Alerts from a Clinical Decision Support System, MedGuard, for Patient Safety
T2 - 18th World Congress on Medical and Health Informatics: One World, One Health - Global Partnership for Digital Innovation, MEDINFO 2021
AU - Poly, Tahmina Nasrin
AU - Islam, Md Mohaimenul
AU - Li, Yu Chuan Jack
N1 - Publisher Copyright:
© 2022 International Medical Informatics Association (IMIA) and IOS Press.
PY - 2022/6
Y1 - 2022/6
N2 - Clinical decision support systems have been widely used in healthcare, yet few studies have concurrently measured the clinical effectiveness of CDSSs, and the appropriateness of alerts with physicians' response to alerts. We conducted a retrospective analysis of prescriptions caused disease-medication related alerts. Medication orders for outpatients' prescriptions, all aged group were included in this study. All the prescriptions were reviewed, and medication orders compared with a widely used medication reference (UpToDate) and other standard guidelines. We reviewed 1,409 CDS alerts (2.67% alert rate) on 52,654 prescriptions ordered during the study period. 545 (38.70%) of alerts were overridden. Override appropriateness was 2.20% overall. However, the rate of alert acceptance was higher, ranging from 11.11 to 92.86%. The MedGuard system had a lower overridden rate than other systems reported in previous studies. The acceptance rate of alerts by physicians was high. Moreover, false-positive rate was low. The MedGuard system has the potential to reduce alert fatigue and to minimize the risk of patient harm.
AB - Clinical decision support systems have been widely used in healthcare, yet few studies have concurrently measured the clinical effectiveness of CDSSs, and the appropriateness of alerts with physicians' response to alerts. We conducted a retrospective analysis of prescriptions caused disease-medication related alerts. Medication orders for outpatients' prescriptions, all aged group were included in this study. All the prescriptions were reviewed, and medication orders compared with a widely used medication reference (UpToDate) and other standard guidelines. We reviewed 1,409 CDS alerts (2.67% alert rate) on 52,654 prescriptions ordered during the study period. 545 (38.70%) of alerts were overridden. Override appropriateness was 2.20% overall. However, the rate of alert acceptance was higher, ranging from 11.11 to 92.86%. The MedGuard system had a lower overridden rate than other systems reported in previous studies. The acceptance rate of alerts by physicians was high. Moreover, false-positive rate was low. The MedGuard system has the potential to reduce alert fatigue and to minimize the risk of patient harm.
KW - alert fatigue
KW - Clinical decision support
KW - disease-drug interaction
KW - patients safety
UR - http://www.scopus.com/inward/record.url?scp=85131500596&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85131500596&partnerID=8YFLogxK
U2 - 10.3233/SHTI220089
DO - 10.3233/SHTI220089
M3 - Conference contribution
C2 - 35673028
AN - SCOPUS:85131500596
T3 - Studies in Health Technology and Informatics
SP - 326
EP - 329
BT - MEDINFO 2021
A2 - Otero, Paula
A2 - Scott, Philip
A2 - Martin, Susan Z.
A2 - Huesing, Elaine
PB - IOS Press BV
Y2 - 2 October 2021 through 4 October 2021
ER -