Clinical characteristics of patients with exercise-induced ST-segment elevation without prior myocardial infarction

Ming Jui Hung, Ming Yow Hung, Chi Wen Cheng, Ning I. Yang, Wen Jin Cherng

Research output: Contribution to journalArticlepeer-review

20 Citations (Scopus)


Background: Exercise-induced ST-segment elevation is a relatively uncommon problem and occurs more frequently in patients who have had a myocardial infarction. Data is limited on the characteristics of Taiwanese patients without prior myocardial infarction who develop exercise-induced ST-segment elevation. Methods and Results: Exercise-induced ST-segment elevation developed in 9 of 6,147 consecutive patients without myocardial infarction who underwent treadmill exercise testing at out institution over a 4-year period. The clinical and angiographic characteristics of these patients were studied. Angiographically normal coronary arteries with coronary vasospasm were found in 5 patients, hemodynamically significant coronary stenosis was found in 3 patients, and coexisting spasm in angiographically normal coronary arteries combined with hemodynamically significant coronary stenosis in the different vessel was found in 1 patient. During a median follow-up of 71 months, 2 patients with coronary vasospasm developed recurrent angina after self-discontinuation of calcium antagonists and 2 patients (1 with coronary vasospasm and 1 with hemodynamically significant coronary stenosis) died of cardiac causes before arrival at the emergency department. Conclusion Coronary vasospasm was a more common underlying pathology of exercise-induced ST-segment elevation in this Taiwanese cohort. Coronary angiography ± intracoronary ergonovine provocation testing is necessary in these patients to identify the underlying pathology and appropriate treatment.

Original languageEnglish
Pages (from-to)254-261
Number of pages8
JournalCirculation Journal
Issue number3
Publication statusPublished - 2006
Externally publishedYes


  • Coronary vasospasm
  • Exercise

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


Dive into the research topics of 'Clinical characteristics of patients with exercise-induced ST-segment elevation without prior myocardial infarction'. Together they form a unique fingerprint.

Cite this