Cleaved but not endogenous secretory RAGE is associated with outcome in acute ischemic stroke

Sung Chun Tang; Shin Joe Yeh; Li Kai Tsai; Chaur Jong Hu; Li Ming Lien; Giia Sheun Peng; Wei Shiung Yang; Hung Yi Chiou; Jiann Shing Jeng

doi:10.1212/WNL.0000000000002287

Cleaved but not endogenous secretory RAGE is associated with outcome in acute ischemic stroke

Sung Chun Tang, Shin Joe Yeh, Li Kai Tsai, Chaur Jong Hu, Li Ming Lien, Giia Sheun Peng, Wei Shiung Yang, Hung Yi Chiou, Jiann Shing Jeng

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Abstract

Objective: To investigate the expression patterns of 2 soluble isoforms of receptor for advanced glycation end-product (RAGE), including endogenous secretory RAGE (esRAGE) and cleaved RAGE (cRAGE), and their associations with outcome in acute ischemic stroke (IS). Methods: Acute IS patients (n = 106) and age- and sex-matched controls (n = 150) were recruited. Plasma levels of total soluble RAGE (sRAGE) and esRAGE in patients at

Original language	English
Pages (from-to)	270-276
Number of pages	7
Journal	Neurology
Volume	86
Issue number	3
DOIs	https://doi.org/10.1212/WNL.0000000000002287
Publication status	Published - Jan 19 2016

ASJC Scopus subject areas

Clinical Neurology

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abstract = "Objective: To investigate the expression patterns of 2 soluble isoforms of receptor for advanced glycation end-product (RAGE), including endogenous secretory RAGE (esRAGE) and cleaved RAGE (cRAGE), and their associations with outcome in acute ischemic stroke (IS). Methods: Acute IS patients (n = 106) and age- and sex-matched controls (n = 150) were recruited. Plasma levels of total soluble RAGE (sRAGE) and esRAGE in patients at ",

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note = "Publisher Copyright: {\textcopyright} 2015 American Academy of Neurology.",

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doi = "10.1212/WNL.0000000000002287",

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T1 - Cleaved but not endogenous secretory RAGE is associated with outcome in acute ischemic stroke

AU - Tang, Sung Chun

AU - Yeh, Shin Joe

AU - Tsai, Li Kai

AU - Hu, Chaur Jong

AU - Lien, Li Ming

AU - Peng, Giia Sheun

AU - Yang, Wei Shiung

AU - Chiou, Hung Yi

AU - Jeng, Jiann Shing

PY - 2016/1/19

Y1 - 2016/1/19

N2 - Objective: To investigate the expression patterns of 2 soluble isoforms of receptor for advanced glycation end-product (RAGE), including endogenous secretory RAGE (esRAGE) and cleaved RAGE (cRAGE), and their associations with outcome in acute ischemic stroke (IS). Methods: Acute IS patients (n = 106) and age- and sex-matched controls (n = 150) were recruited. Plasma levels of total soluble RAGE (sRAGE) and esRAGE in patients at

AB - Objective: To investigate the expression patterns of 2 soluble isoforms of receptor for advanced glycation end-product (RAGE), including endogenous secretory RAGE (esRAGE) and cleaved RAGE (cRAGE), and their associations with outcome in acute ischemic stroke (IS). Methods: Acute IS patients (n = 106) and age- and sex-matched controls (n = 150) were recruited. Plasma levels of total soluble RAGE (sRAGE) and esRAGE in patients at

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JO - Neurology

JF - Neurology

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ER -

Cleaved but not endogenous secretory RAGE is associated with outcome in acute ischemic stroke

Abstract

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