Circuit Integration Initiation of New Hippocampal Neurons in the Adult Brain

Chih Hao Yang; Adrian Di Antonio; Gregory W. Kirschen; Parul Varma; Jenny Hsieh; Shaoyu Ge

doi:10.1016/j.celrep.2019.12.084

Circuit Integration Initiation of New Hippocampal Neurons in the Adult Brain

Chih Hao Yang, Adrian Di Antonio, Gregory W. Kirschen, Parul Varma, Jenny Hsieh, Shaoyu Ge

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

Yang et al. show that prior to circuit integration, adult-born dentate granule cells undergo horizontal-to-radial transitioning, which is regulated by sphingolipid signaling via sphingosine-1-phosphate receptor 1.

Original language	English
Pages (from-to)	959-968.e3
Journal	Cell Reports
Volume	30
Issue number	4
DOIs	https://doi.org/10.1016/j.celrep.2019.12.084
Publication status	Published - Jan 28 2020

Keywords

adult hippocampal neurogenesis
circuit integration initiation
dentate granule cell
electrophysiological maturation
environmental enrichment
G protein-coupled receptor
hippocampus behavior-engaged activation
lipidomics
sphingosine-1-phosphate receptor 1

ASJC Scopus subject areas

General Biochemistry,Genetics and Molecular Biology

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10.1016/j.celrep.2019.12.084

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title = "Circuit Integration Initiation of New Hippocampal Neurons in the Adult Brain",

abstract = "Yang et al. show that prior to circuit integration, adult-born dentate granule cells undergo horizontal-to-radial transitioning, which is regulated by sphingolipid signaling via sphingosine-1-phosphate receptor 1.",

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author = "Yang, {Chih Hao} and {Di Antonio}, Adrian and Kirschen, {Gregory W.} and Parul Varma and Jenny Hsieh and Shaoyu Ge",

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AU - Di Antonio, Adrian

AU - Kirschen, Gregory W.

AU - Varma, Parul

AU - Hsieh, Jenny

AU - Ge, Shaoyu

PY - 2020/1/28

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KW - dentate granule cell

KW - electrophysiological maturation

KW - environmental enrichment

KW - G protein-coupled receptor

KW - hippocampus behavior-engaged activation

KW - lipidomics

KW - sphingosine-1-phosphate receptor 1

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Circuit Integration Initiation of New Hippocampal Neurons in the Adult Brain

Abstract

Keywords

ASJC Scopus subject areas

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