Characterization of Two Novel Cell Lines with Distinct Heterogeneity Derived from a Single Human Bile Duct Carcinoma

Agriculture & Biology

• bile ducts 100%
• carcinoma 83%
• cell lines 59%
• cells 25%
• neoplasm cells 16%
• gelatinase B 8%
• gelatinase A 8%
• vascular endothelial growth factors 8%
• vimentin 7%
• metastasis 7%
• drug resistance 7%
• cell aggregates 6%
• anaerobic conditions 6%
• stem cells 6%
• drug therapy 6%
• karyotyping 5%
• snails 5%
• hypoxia 5%
• therapeutics 4%
• neoplasms 4%
• protein synthesis 4%
• molecular cloning 4%
• phenotype 4%
• mice 3%
• tissues 2%
• genes 2%
• methodology 1%

Medicine & Life Sciences

• Bile Ducts 81%
• Carcinoma 52%
• Cell Line 47%
• gemcitabine 11%
• Neoplasms 6%
• Radiation Tolerance 6%
• Matrix Metalloproteinase 2 5%
• Chemoradiotherapy 5%
• Neoplastic Stem Cells 5%
• Epithelial-Mesenchymal Transition 5%
• Vimentin 5%
• Karyotype 5%
• Matrix Metalloproteinases 5%
• Nude Mice 5%
• Organism Cloning 4%
• Drug Resistance 4%
• Vascular Endothelial Growth Factor A 4%
• Hypoxia 4%
• Radiation 3%
• Neoplasm Metastasis 3%
• Phenotype 3%
• Drug Therapy 3%
• Recurrence 3%
• Messenger RNA 3%
• Genes 2%
• Proteins 1%
• Therapeutics 0%

Chemical Compounds

• Heterogeneity 73%
• Gemcitabine 59%
• Marker 34%
• Tumorigenic 29%
• Monolayer 14%
• Resistance 12%
• Protein 8%