Cessation of nail growth following Bajiaolian intoxication

Shang Lin Chou, Ming Yueh Chou, Wei Fong Kao, David H.T. Yen, Chun I. Huang, Chen Hsen Lee

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)


Bajiaolian (Dysosma pleianthum), a species in the Mayapple family (Podophyllum pelatum), has been widely used as a traditional Chinese herbal medication for the remedies of snake bite, tumor growth, post-partum recovery, and acne. It has also been used in western medicine, especially topically for various skin lesions. Both oral ingestion and dermal application may result in severe toxicity. The clinical presentations reported after Bajiaolian poisoning include nausea, vomiting, diarrhea, abdominal cramps, tachycardia, orthostatic hypotension, paralytic ileus, urinary retention, hepatorenal dysfunction, leukocytosis followed by leukopenia, thrombocytopenia, prolonged areflexia, prolonged paraethesia and sensory ataxia, dizziness, fever, memory impairment, hallucinations, paranoia, convulsion, fainting, and coma. There are no previous reports in the literature about the cessation of nail growth as a clinical presentation following Bajiaolian poisoning. We present a case of nail growth that was halted for more than seven years after a single case of Bajiaolian poisoning.

Original languageEnglish
Pages (from-to)159-163
Number of pages5
JournalClinical Toxicology
Issue number2
Publication statusPublished - Feb 2008
Externally publishedYes


  • Bajiaolian
  • Nail growth
  • Podophyllotoxin

ASJC Scopus subject areas

  • Toxicology


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