TY - JOUR
T1 - Cefepime MIC as a predictor of the extended-spectrum β-lactamase type in Klebsiella pneumoniae, Taiwan
AU - Yu, Wen Liang
AU - Pfaller, Michael A.
AU - Winokur, Patricia L.
AU - Jones, Ronald N.
PY - 2002
Y1 - 2002
N2 - To guide selection of carbapenems or fourth-generation cephalosporins as therapy, 110 Klebsiella pneumoniae isolates with extended-spectrum β-lactamases from Taiwan were characterized by phenotypic (MICs), molecular, and chemical methods. MIC patterns of ceftazidime and cefepime clearly differentiate strains treatable by cefepime and those capable of efficiently hydrolyzing available cephalosporins (CTX-M series and SHV-types). Continued use of cefepime appears to be a treatment option in cases for which MIC results are available and interpreted by the criteria presented.
AB - To guide selection of carbapenems or fourth-generation cephalosporins as therapy, 110 Klebsiella pneumoniae isolates with extended-spectrum β-lactamases from Taiwan were characterized by phenotypic (MICs), molecular, and chemical methods. MIC patterns of ceftazidime and cefepime clearly differentiate strains treatable by cefepime and those capable of efficiently hydrolyzing available cephalosporins (CTX-M series and SHV-types). Continued use of cefepime appears to be a treatment option in cases for which MIC results are available and interpreted by the criteria presented.
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U2 - 10.3201/eid0805.010346
DO - 10.3201/eid0805.010346
M3 - Article
C2 - 11996691
AN - SCOPUS:0036093612
SN - 1080-6040
VL - 8
SP - 522
EP - 524
JO - Emerging Infectious Diseases
JF - Emerging Infectious Diseases
IS - 5
ER -
