CD8+CD122+ T cell homeostasis is controlled by different levels of IL-15 trans-presentation

Gilbert Aaron Lee; Nan Shih Liao

doi:10.1016/j.jmii.2020.06.005

CD8⁺CD122⁺ T cell homeostasis is controlled by different levels of IL-15 trans-presentation

Gilbert Aaron Lee
, Nan Shih Liao

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

The homeostasis of CD8⁺CD122⁺ T cell requires IL-15 trans-presentation. We use Il15ra mutant mice and bone marrow chimeras to assess the role of IL-15 trans-presentation level in CD8⁺CD122⁺ T cells homeostasis. We demonstrate that CD8⁺CD122⁺ T cells require different levels of IL-15 trans-presentation to support their homeostasis.

Original language	English
Pages (from-to)	514-517
Number of pages	4
Journal	Journal of Microbiology, Immunology and Infection
Volume	54
Issue number	3
DOIs	https://doi.org/10.1016/j.jmii.2020.06.005
Publication status	Published - Jun 2021

Keywords

CD8CD122 T cell homeostasis
IL-15

ASJC Scopus subject areas

Immunology and Allergy
General Immunology and Microbiology
Microbiology (medical)
Infectious Diseases

Access to Document

10.1016/j.jmii.2020.06.005

Cite this

@article{139594bcd31642338c6990347ac01a26,

title = "CD8+CD122+ T cell homeostasis is controlled by different levels of IL-15 trans-presentation",

abstract = "The homeostasis of CD8+CD122+ T cell requires IL-15 trans-presentation. We use Il15ra mutant mice and bone marrow chimeras to assess the role of IL-15 trans-presentation level in CD8+CD122+ T cells homeostasis. We demonstrate that CD8+CD122+ T cells require different levels of IL-15 trans-presentation to support their homeostasis.",

keywords = "CD8CD122 T cell homeostasis, IL-15",

author = "Lee, \{Gilbert Aaron\} and Liao, \{Nan Shih\}",

note = "Funding Information: This work was supported by Academia Sinica ( 20-2d ) and Taipei Medical University Hospital ( 107TMUH SP-01 ). Publisher Copyright: {\textcopyright} 2020 Copyright: Copyright 2020 Elsevier B.V., All rights reserved.",

year = "2021",

month = jun,

doi = "10.1016/j.jmii.2020.06.005",

language = "English",

volume = "54",

pages = "514--517",

journal = "Journal of Microbiology, Immunology and Infection",

issn = "1684-1182",

publisher = "Lippincott Williams \& Wilkins Asia",

number = "3",

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AU - Lee, Gilbert Aaron

AU - Liao, Nan Shih

N1 - Funding Information: This work was supported by Academia Sinica ( 20-2d ) and Taipei Medical University Hospital ( 107TMUH SP-01 ). Publisher Copyright: © 2020 Copyright: Copyright 2020 Elsevier B.V., All rights reserved.

PY - 2021/6

Y1 - 2021/6

N2 - The homeostasis of CD8+CD122+ T cell requires IL-15 trans-presentation. We use Il15ra mutant mice and bone marrow chimeras to assess the role of IL-15 trans-presentation level in CD8+CD122+ T cells homeostasis. We demonstrate that CD8+CD122+ T cells require different levels of IL-15 trans-presentation to support their homeostasis.

AB - The homeostasis of CD8+CD122+ T cell requires IL-15 trans-presentation. We use Il15ra mutant mice and bone marrow chimeras to assess the role of IL-15 trans-presentation level in CD8+CD122+ T cells homeostasis. We demonstrate that CD8+CD122+ T cells require different levels of IL-15 trans-presentation to support their homeostasis.

KW - CD8CD122 T cell homeostasis

KW - IL-15

UR - https://www.scopus.com/pages/publications/85087219058

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DO - 10.1016/j.jmii.2020.06.005

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JF - Journal of Microbiology, Immunology and Infection

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