Cardiovascular Disease Burden Attributable to High Body Mass Index in Taiwan

Tzu Lin Yeh, Yi Hsuan Roger Chen, Hsin Yin Hsu, Ming Chieh Tsai, Yun Chun Wu, Wei Cheng Lo, Tzu Hsuan Huang, Bo Chen Liu, Hsien Ho Lin, Kuo Liong Chien

Research output: Contribution to journalArticlepeer-review


Background: Studies on disease burden in Taiwan are lacking. We aimed to quantify the burden of cardiovascular disease (CVD) attributable to high body mass index (BMI) in Taiwan. Methods: Using a comparative risk assessment approach from the Global Burden of Disease study, we estimated the population attributable fraction (PAF), attributable CVD burden, and disability-adjusted life years (DALYs) according to sex, age, and area of residence in Taiwan. The BMI distribution for the population was obtained from the National Health Interview Survey in 2013. CVD was defined as an ischemic heart disease or stroke. Results: The attributable PAF for CVD from high BMI was 18.0% (19.6% in men and 15.6% in women), and it was highest (42.7%) in those aged 25-30 years. Adults aged 60-65 years had the highest absolute DALYs (11,546). The average relative age-standardized attributable burden was 314 DALYs per 100,000 person-years, and it was highest in those aged 75-80 years (1,407 DALYs per 100,000 person-years). Those living in Taitung County had the highest PAF of 21.9% and the highest age-standardized attributable burden (412 DALYs). Conclusions: In Taiwan, an 18% reduction in CVDs could be achieved if obesity/overweight was prevented. Prevention was most effective in early adulthood. The absolute CVD burden from obesity/overweight was highest in middle-aged men, and the relative burden was highest in older adults. Resource allocation in targeted populations and specific areas to eliminate CVD and health inequities is urgently required.

Original languageEnglish
Pages (from-to)628-642
Number of pages15
JournalActa Cardiologica Sinica
Issue number4
Publication statusPublished - Jul 2023


  • Attributable disease burden
  • Cardiovascular disease
  • Comparative risk assessment
  • High body mass index
  • Population attributable fraction

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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