Cardiac conductive disturbance in patients with polycystic ovary syndrome

Jen Hung Huang, Jen Chen Tsai, Ming I. Hsu, Yi Jen Chen

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


Background.Polycystic ovary syndrome (PCOS) is the most common endocrine abnormality of reproductive-aged women and increases the risk of cardiovascular disease. However, the effects of PCOS on electrocardiograms (ECGs) are not fully elucidated. The aim of this study was to evaluate the characteristics of ECGs in patients with PCOS. Methods.This study included 24 patients with PCOS and 12 patients without PCOS. The heart rate, PR interval, QRS duration, Sokolow-Lyon voltage (SV1 + RV5/6), Cornell voltage (RaVL + SV3), QT interval and QTc interval were measured in 12-lead ECGs. Results.The QRS duration was wider in patients with PCOS than those without PCOS (91±8 vs. 81±10ms, p<0.05). The heart rate, PR interval, Sokolow-Lyon voltage, product of the QRS duration times Cornell voltage combination, QT interval, QTc interval, QT dispersion and QTc dispersion were similar between the two groups. Conclusions.PCOS is associated with a widening QRS duration, which may contribute to its increased cardiovascular risks.

Original languageEnglish
Pages (from-to)883-888
Number of pages6
JournalGynecological Endocrinology
Issue number12
Publication statusPublished - Dec 2010


  • Electrocardiogram
  • QRS duration
  • QT dispersion
  • autonomic dysfunction
  • polycystic ovary syndrome

ASJC Scopus subject areas

  • Endocrinology
  • Obstetrics and Gynaecology
  • Endocrinology, Diabetes and Metabolism


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