Cancer-Associated Thrombosis: A Taiwanese Perspective on Therapeutic Options with Focus on Non-Vitamin K Antagonist Oral Anticoagulants

Yu Yun Shao, Ching Liang Ho, Cheng Shyong Chang, Chia Lun Chang, Jen Kuang Lee, Hung Ju Lin, Hui Hua Hsiao, Ta Chung Chao, Ching Yeh Lin, Chuang Chi Liaw

Research output: Contribution to journalReview articlepeer-review

1 Citation (Scopus)

Abstract

Cancer-associated thrombosis (CAT) is a common complication of malignancies. Patients with CAT are at risk of venous thromboembolism recurrence, but also at risk of bleeding while anticoagulated. Taiwanese patients are perceived to have a lower incidence of CAT, likely leading to false reassurance for Taiwanese patients with cancer. Because of this, oncologists and cardiologists from multiple medical institutions in Taiwan have set forth to provide clinical consensus guidelines on the management of CAT, based on local clinical practices and guided by predominant international clinical practice guidelines. This paper aims to describe the current disease burden of cancer-associated venous thromboembolism in Taiwanese cancer patients, and discusses the unmet needs and gaps in the management of this medical complication. It also outlines diagnostic and management strategies relevant to the different treatment options available, such as non-vitamin K antagonist oral anticoagulants.

Original languageEnglish
Pages (from-to)242-253
Number of pages12
JournalActa Cardiologica Sinica
Volume39
Issue number2
DOIs
Publication statusPublished - Mar 2023

Keywords

  • Cancer-associated thrombosis
  • Deep venous thromboembolism
  • Evidence-based guidelines
  • Non-vitamin K antagonist oral anticoagulants
  • Pulmonary embolism

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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