C-reactive protein concentration as a significant correlate for metabolic syndrome: A Chinese population-based study

Tsan Yang; Chi Hong Chu; Po Chien Hsieh; Chih Hsung Hsu; Yu Ching Chou; Shih Hsien Yang; Chyi-Huey Bai; San Lin You; Lee Ching Hwang; Tieh Chi Chung; Chien An Sun

doi:10.1007/s12020-012-9743-7

C-reactive protein concentration as a significant correlate for metabolic syndrome: A Chinese population-based study

Tsan Yang, Chi Hong Chu, Po Chien Hsieh, Chih Hsung Hsu, Yu Ching Chou, Shih Hsien Yang, Chyi-Huey Bai, San Lin You, Lee Ching Hwang, Tieh Chi Chung, Chien An Sun

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28 Citations (Scopus)

Abstract

Increasing evidence suggests that chronic, low-grade inflammation may be a common soil involving the pathogenesis of metabolic syndrome (MetS) and cardiovascular disease. We examined the association between C-reactive protein (CRP) concentration, an extensively studied biomarker of low-grade inflammation, and the MetS in a representative sample of Chinese adults in Taiwan. We performed a cross-sectional analysis of data from 4234 subjects [mean (±SD) age, 47.1 (±18.2) years; 46.4 % males] who participated in a population-based survey on prevalences of hypertension, hyperglycemia, and hyperlipidemia in Taiwan. CRP levels were measured by the immunoturbidimetric CRP-latex high-sensitivity assay. The MetS was defined by an unified criteria set by several major organizations. Odds ratios (ORs) and 95 % confidence intervals (CIs) were calculated with logistic regression model. Overall, there were 938 subjects with MetS among 4,234 participants, resulting in a prevalence rate of 22.1 %. A significantly progressive increase in the prevalence of MetS across quartiles of CRP was observed (p for trend

Original language	English
Pages (from-to)	351-359
Number of pages	9
Journal	Endocrine
Volume	43
Issue number	2
DOIs	https://doi.org/10.1007/s12020-012-9743-7
Publication status	Published - Apr 2013

Keywords

C-reactive protein
Chinese
Cross-sectional study
Inflammation
Metabolic syndrome

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Endocrinology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/s12020-012-9743-7

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title = "C-reactive protein concentration as a significant correlate for metabolic syndrome: A Chinese population-based study",

abstract = "Increasing evidence suggests that chronic, low-grade inflammation may be a common soil involving the pathogenesis of metabolic syndrome (MetS) and cardiovascular disease. We examined the association between C-reactive protein (CRP) concentration, an extensively studied biomarker of low-grade inflammation, and the MetS in a representative sample of Chinese adults in Taiwan. We performed a cross-sectional analysis of data from 4234 subjects [mean (±SD) age, 47.1 (±18.2) years; 46.4 % males] who participated in a population-based survey on prevalences of hypertension, hyperglycemia, and hyperlipidemia in Taiwan. CRP levels were measured by the immunoturbidimetric CRP-latex high-sensitivity assay. The MetS was defined by an unified criteria set by several major organizations. Odds ratios (ORs) and 95 % confidence intervals (CIs) were calculated with logistic regression model. Overall, there were 938 subjects with MetS among 4,234 participants, resulting in a prevalence rate of 22.1 %. A significantly progressive increase in the prevalence of MetS across quartiles of CRP was observed (p for trend ",

keywords = "C-reactive protein, Chinese, Cross-sectional study, Inflammation, Metabolic syndrome",

author = "Tsan Yang and Chu, {Chi Hong} and Hsieh, {Po Chien} and Hsu, {Chih Hsung} and Chou, {Yu Ching} and Yang, {Shih Hsien} and Chyi-Huey Bai and You, {San Lin} and Hwang, {Lee Ching} and Chung, {Tieh Chi} and Sun, {Chien An}",

note = "Funding Information: Acknowledgments This study was supported by a grant from the Bureau of Health Promotion, Department of Health (DOH95-HP-2103), Executive Yuan, Taiwan, ROC.",

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T1 - C-reactive protein concentration as a significant correlate for metabolic syndrome

T2 - A Chinese population-based study

AU - Yang, Tsan

AU - Chu, Chi Hong

AU - Hsieh, Po Chien

AU - Hsu, Chih Hsung

AU - Chou, Yu Ching

AU - Yang, Shih Hsien

AU - Bai, Chyi-Huey

AU - You, San Lin

AU - Hwang, Lee Ching

AU - Chung, Tieh Chi

AU - Sun, Chien An

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PY - 2013/4

Y1 - 2013/4

N2 - Increasing evidence suggests that chronic, low-grade inflammation may be a common soil involving the pathogenesis of metabolic syndrome (MetS) and cardiovascular disease. We examined the association between C-reactive protein (CRP) concentration, an extensively studied biomarker of low-grade inflammation, and the MetS in a representative sample of Chinese adults in Taiwan. We performed a cross-sectional analysis of data from 4234 subjects [mean (±SD) age, 47.1 (±18.2) years; 46.4 % males] who participated in a population-based survey on prevalences of hypertension, hyperglycemia, and hyperlipidemia in Taiwan. CRP levels were measured by the immunoturbidimetric CRP-latex high-sensitivity assay. The MetS was defined by an unified criteria set by several major organizations. Odds ratios (ORs) and 95 % confidence intervals (CIs) were calculated with logistic regression model. Overall, there were 938 subjects with MetS among 4,234 participants, resulting in a prevalence rate of 22.1 %. A significantly progressive increase in the prevalence of MetS across quartiles of CRP was observed (p for trend

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KW - Cross-sectional study

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KW - Metabolic syndrome

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C-reactive protein concentration as a significant correlate for metabolic syndrome: A Chinese population-based study

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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