Byakangelicol, isolated from Angelica dahurica, inhibits both the activity and induction of cyclooxygenase-2 in human pulmonary epithelial cells

Medicine & Life Sciences

• byakangelicol 100%
• Angelica 69%
• Cyclooxygenase 2 47%
• Epithelial Cells 32%
• Interleukin-1 29%
• Lung 24%
• Dinoprostone 14%
• Mitogen-Activated Protein Kinases 9%
• Cytosol 9%
• Enzymes 8%
• prolinedithiocarbamate 7%
• pyrrolidine dithiocarbamic acid 7%
• N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide 7%
• 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one 5%
• Cyclooxygenase 2 Inhibitors 5%
• A549 Cells 5%
• Mitogen-Activated Protein Kinase Kinases 5%
• Extracellular Signal-Regulated MAP Kinases 5%
• Protein Kinase Inhibitors 5%
• Anti-Inflammatory Agents 3%
• Cell Line 2%
• Inflammation 2%
• DNA 2%
• Pharmaceutical Preparations 2%
• Proteins 1%
• Therapeutics 1%

Chemical Compounds

• Byakangelicol 92%
• Prostaglandin E2 20%
• NS-398 9%
• EC 2.7.12.2 (Mitogen-Activated Protein Kinase Kinase) Inhibitor 8%
• Pyrrolidine Dithiocarbamate 7%
• Cyclooxygenase 2 Inhibitor 7%
• Anti-Inflammatory Drug 6%
• Protein 6%