TY - JOUR
T1 - Burkitt tumor
T2 - Tissue culture, cytogenetic and virus studies
AU - Stewart, Sarah E.
AU - Lovelace, Elizabeth
AU - Whang, Jacqueline J.
AU - Ngu, V. Anomah
PY - 1965/1/1
Y1 - 1965/1/1
N2 - Tumor cells that retained their original histology were grown from a biopsy taken from a 7-year-ofd male with a Burkitt tumor. The cells grew in suspension, usually in clumps varying from a few to hundreds of cells in a free-floating mass. This cell line was designated SL1. A herpes-like virus, which caused some cell degeneration of the tumor cells in culture, was observed by electron microscopy. Supernatant fluids from the SL1 cultures failed to produce a cytopathogenic effect in inoculated cell lines. A specific chromosome alteration was observed in the cells from the original tumor and in the cultured tumor cells.
AB - Tumor cells that retained their original histology were grown from a biopsy taken from a 7-year-ofd male with a Burkitt tumor. The cells grew in suspension, usually in clumps varying from a few to hundreds of cells in a free-floating mass. This cell line was designated SL1. A herpes-like virus, which caused some cell degeneration of the tumor cells in culture, was observed by electron microscopy. Supernatant fluids from the SL1 cultures failed to produce a cytopathogenic effect in inoculated cell lines. A specific chromosome alteration was observed in the cells from the original tumor and in the cultured tumor cells.
UR - http://www.scopus.com/inward/record.url?scp=26444590218&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=26444590218&partnerID=8YFLogxK
U2 - 10.1093/jnci/34.2.319
DO - 10.1093/jnci/34.2.319
M3 - Article
C2 - 14293797
AN - SCOPUS:26444590218
SN - 0027-8874
VL - 34
SP - 319
EP - 327
JO - Journal of the National Cancer Institute
JF - Journal of the National Cancer Institute
IS - 2
ER -
