Brain stem cavernous malformations

A. P H Huang, Jui Sheng Chen, Chi Cheng Yang, Kuo Chuan Wang, Shih Hung Yang, Dar Ming Lai, Yong Kwang Tu

Research output: Contribution to journalArticlepeer-review

29 Citations (Scopus)


We retrospectively reviewed the clinical experience of 30 patients with brain stem cavernous malformations (BSCM) treated operatively and non-operatively at our hospital between 1983 and 2005 to elucidate the natural history of BSCM and the factors that affect surgical outcome. Inpatient charts, imaging studies, operative records, and follow-up results were evaluated. The average follow up was 48.5 months. Twenty-two patients (73.3%) received surgical extirpation and of these 86.4% improved or stabilized and 13.6% deteriorated with permanent or severe morbidity. There was no mortality. Size, preoperative status, and surgical timing were factors related to surgical outcome. In the non-operative group, 50% of the patients were the same or better, 25% deteriorated, and 25% died. With appropriate patient selection, resection of BSCM can be achieved with acceptable morbidity compared with the ominous natural history of these lesions.

Original languageEnglish
Pages (from-to)74-79
Number of pages6
JournalJournal of Clinical Neuroscience
Issue number1
Publication statusPublished - Jan 1 2010
Externally publishedYes


  • Brain stem hemorrhage
  • Cavernoma
  • Cavernous malformation

ASJC Scopus subject areas

  • Clinical Neurology
  • Physiology (medical)
  • Neurology


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