Bladder Pain Syndrome/Interstitial Cystitis Is Associated with Hyperthyroidism

Shiu Dong Chung, Shih Ping Liu, Ching Chun Lin, Hsien-Chang Li, Herng Ching Lin

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)


Background:Although the etiology of bladder pain syndrome/interstitial cystitis (BPS/IC) is still unclear, a common theme with BPS/IC patients is comorbid disorders which are related to the autonomic nervous system that connects the nervous system to end-organs. Nevertheless, no study to date has reported the association between hyperthyroidism and BPS/IC. In this study, we examined the association of IC/BPS with having previously been diagnosed with hyperthyroidism in Taiwan.Design:Data in this study were retrieved from the Longitudinal Health Insurance Database. Our study consisted of 736 female cases with BPS/IC and 2208 randomly selected female controls. We performed a conditional logistic regression to calculate the odds ratio (OR) for having previously been diagnosed with hyperthyroidism between cases and controls.Results:Of the 2944 sampled subjects, there was a significant difference in the prevalence of prior hyperthyroidism between cases and controls (3.3% vs. 1.5%, p

Original languageEnglish
Article numbere72284
JournalPLoS One
Issue number8
Publication statusPublished - Aug 21 2013

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)


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