Bladder pain syndrome/interstitial cystitis is associated with asthma: A case-control study

Shiu Dong Chung, Chung Chien Huang, Herng Ching Lin, Li Ting Kao

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)


Objective: Although asthma and bladder pain syndrome/interstitial cystitis (BPS/IC) are considered to share similar pathophysiological pathways, the relationship between asthma and BPS/IC is uncertain. This case-control study aimed to investigate the relationship between prior asthma and BPS/IC using a large database in Taiwan. Materials and methods: This study used data from the Taiwan Longitudinal Health Insurance Database 2005. We identified 500 female patients with BPS/IC as cases and 500 propensity score-matched females without BPS/IC as controls. We conducted logistic regressions to estimate the odds ratio (OR) and 95% confidence interval (CI) for prior asthma between cases and controls. Results: Results indicated that 143 (14.30%) of the total sampled patients had received a prior diagnosis of asthma. Moreover, prior asthma was found in 86 (17.20%) cases and 57 (11.40%) controls. The OR of prior asthma for cases was 1.61 (95%CI: 1.13-2.32) compared to propensity score-matched controls. Additionally, the ORs of prior asthma for females with BPS/IC aged 18-59 and ≥60 years were 1.72 (95%CI: 1.11-2.69) and 1.40 (95%CI: 0.74-2.62), respectively, compared to controls. Conclusions: We concluded that prior asthma was significantly associated with BPS/IC in a female Taiwanese population.

Original languageEnglish
Pages (from-to)1773-1778
Number of pages6
JournalNeurourology and Urodynamics
Issue number5
Publication statusPublished - Jun 1 2018


  • allergy
  • asthma
  • bladder
  • bladder pain syndrome
  • interstitial cystitis

ASJC Scopus subject areas

  • Clinical Neurology
  • Urology


Dive into the research topics of 'Bladder pain syndrome/interstitial cystitis is associated with asthma: A case-control study'. Together they form a unique fingerprint.

Cite this