Biomarkers in Acute Kidney Injury

Cai-mei Zheng, Min Tser Liao, Mei Yu Lin, Lan Lo, Chia-Chao Wu, Yung-Ho Hsu, Yuh-Feng Lin, Kuo-Cheng Lu

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Abstract

Acute kidney injury (AKI) is one of the popular topics of discussions due to increasing development of biomarkers re- cently. The disease progression and prognosis may be determined by these biomarkers detected in blood and urine specimens. Since acute kidney injury is associated with a broad spectrum of disease conditions, prevention and early detection of AKI becomes very important in those clinical settings. Early measurements of AKI biomarkers predict subsequent development of intrinsic AKI, dialysis requirement, duration of intensive care unit stay and finally affect mortality. We, here, discuss the acute kidney injury in different clinical situations and associated natures of biomarkers, which may help us guide to prevent and treat AKI more effectively.
Original languageChinese (Traditional)
Article number3
Pages (from-to)51-60
Number of pages10
JournalOpen Journal of Nephrology
Publication statusPublished - Jan 20 2013

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