Bacteremia in hemodialysis and peritoneal dialysis patients

I. Kuan Wang, Yi Chih Chang, Chih Chia Liang, Feng Rong Chuang, Chiz Tzung Chang, Hsin Hung Lin, Chung Chih Lin, Tzung Hai Yen, Po Chang Lin, Che Yi Chou, Chiu Ching Huang, Wen Chen Tsai, Jin Hua Chen

Research output: Contribution to journalArticlepeer-review

36 Citations (Scopus)


Objective To analyze the incidence rates and risk factors for bacteremia in patients undergoing hemodialysis (HD) and peritoneal dialysis (PD). Methods The records of 898 consecutive patients undergoing dialysis from January 2003 to December 2008 were reviewed retrospectively. Episodes of bacteremia were recorded. China Medical University (Taichung, Taiwan). Results The overall incidence rate of bacteremia was 7.63 per 100 patient-years in HD patients and 3.56 per 100 patient-years in PD patients and it was higher in HD patients each year from 2003 to 2008. S. aureus (27.53%) was the most common pathogen in HD patients, whereas Coagulase-negative Staphylococcus (21.3%) was the most common pathogen in PD patients. Vascular access infection was the most common etiology in HD patients, whereas peritonitis was the most common etiology in PD patients. Older age, shorter dialysis vintage, use of HD rather than PD, current smoker, use of a venous dialysis catheter, presence of diabetes mellitus, higher comorbidity score, and lower serum albumin were significant risk factors for bacteremia. Diabetes mellitus and lower serum albumin were significant risk factors for bacteremia-associated mortality. Conclusion Placement of a permanent access (fistula, graft, or PD catheter) prior to initiation of dialysis, smoking cessation, and better nutritional status (i.e. higher serum albumin) were associated with a reduced risk of bacteremia in dialysis patients. Higher serum albumin was also associated with a reduced bacteremiaassociated mortality.

Original languageEnglish
Pages (from-to)1015-1021
Number of pages7
JournalInternal Medicine
Issue number9
Publication statusPublished - 2012
Externally publishedYes


  • Bacteremia
  • Dialysis
  • End-stage renal disease
  • Incidence rate
  • Mortality

ASJC Scopus subject areas

  • Internal Medicine


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