Autophagy facilitates an IFN-γ response and signal transduction

Yu-Ping Chang; Chia-Ling Chen; Su-O. Chen; Yee-Shin Lin; Cheng-Chieh Tsai; Wei-Ching Huang; Chi-Yun Wang; Chia-Yuan Hsieh; Pui-Ching Choi; Chiou Feng Lin

doi:10.1016/j.micinf.2011.05.008

Autophagy facilitates an IFN-γ response and signal transduction

Yu-Ping Chang, Chia-Ling Chen, Su-O. Chen, Yee-Shin Lin, Cheng-Chieh Tsai, Wei-Ching Huang, Chi-Yun Wang, Chia-Yuan Hsieh, Pui-Ching Choi, Chiou Feng Lin

Research output: Contribution to journal › Short survey › peer-review

13 Citations (Scopus)

Abstract

Autophagy, that is directly triggered by invaded pathogens and indirectly triggered by IFN-γ, acts as a defense by mediating intracellular microbial recognition and clearance. In addition, autophagy contributes to inflammation by facilitating an IFN-γ response and signal transduction. For immune escape, downregulated autophagy may be a strategy used by microbes.

Original language	English
Pages (from-to)	888-894
Number of pages	7
Journal	Microbes and Infection
Volume	13
Issue number	11
DOIs	https://doi.org/10.1016/j.micinf.2011.05.008
Publication status	Published - Oct 2011

Keywords

Autophagy
IFN-γ
Immune escape
Inflammation
Microbe
Signal transduction

ASJC Scopus subject areas

Microbiology
Immunology
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.micinf.2011.05.008

Cite this

@article{86365d881a494c719cdf37a8b8a4d174,

title = "Autophagy facilitates an IFN-γ response and signal transduction",

abstract = "Autophagy, that is directly triggered by invaded pathogens and indirectly triggered by IFN-γ, acts as a defense by mediating intracellular microbial recognition and clearance. In addition, autophagy contributes to inflammation by facilitating an IFN-γ response and signal transduction. For immune escape, downregulated autophagy may be a strategy used by microbes.",

keywords = "Autophagy, IFN-γ, Immune escape, Inflammation, Microbe, Signal transduction",

author = "Yu-Ping Chang and Chia-Ling Chen and Su-O. Chen and Yee-Shin Lin and Cheng-Chieh Tsai and Wei-Ching Huang and Chi-Yun Wang and Chia-Yuan Hsieh and Pui-Ching Choi and Lin, {Chiou Feng}",

year = "2011",

month = oct,

doi = "10.1016/j.micinf.2011.05.008",

language = "English",

volume = "13",

pages = "888--894",

journal = "Microbes and Infection",

issn = "1286-4579",

publisher = "Elsevier Masson s.r.l.",

number = "11",

}

TY - JOUR

T1 - Autophagy facilitates an IFN-γ response and signal transduction

AU - Chang, Yu-Ping

AU - Chen, Chia-Ling

AU - Chen, Su-O.

AU - Lin, Yee-Shin

AU - Tsai, Cheng-Chieh

AU - Huang, Wei-Ching

AU - Wang, Chi-Yun

AU - Hsieh, Chia-Yuan

AU - Choi, Pui-Ching

AU - Lin, Chiou Feng

PY - 2011/10

Y1 - 2011/10

N2 - Autophagy, that is directly triggered by invaded pathogens and indirectly triggered by IFN-γ, acts as a defense by mediating intracellular microbial recognition and clearance. In addition, autophagy contributes to inflammation by facilitating an IFN-γ response and signal transduction. For immune escape, downregulated autophagy may be a strategy used by microbes.

AB - Autophagy, that is directly triggered by invaded pathogens and indirectly triggered by IFN-γ, acts as a defense by mediating intracellular microbial recognition and clearance. In addition, autophagy contributes to inflammation by facilitating an IFN-γ response and signal transduction. For immune escape, downregulated autophagy may be a strategy used by microbes.

KW - Autophagy

KW - IFN-γ

KW - Immune escape

KW - Inflammation

KW - Microbe

KW - Signal transduction

UR - http://www.scopus.com/inward/record.url?scp=80052363444&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=80052363444&partnerID=8YFLogxK

U2 - 10.1016/j.micinf.2011.05.008

DO - 10.1016/j.micinf.2011.05.008

M3 - Short survey

C2 - 21664983

AN - SCOPUS:80052363444

SN - 1286-4579

VL - 13

SP - 888

EP - 894

JO - Microbes and Infection

JF - Microbes and Infection

IS - 11

ER -

Autophagy facilitates an IFN-γ response and signal transduction

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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