Association of Lithium Treatment With Reduced Left Ventricular Concentricity in Patients With Bipolar Disorder

Pao Huan Chen; Cheng Yi Hsiao; Shuo Ju Chiang; Shang Ying Tsai

doi:10.1111/pcn.13497

Association of Lithium Treatment With Reduced Left Ventricular Concentricity in Patients With Bipolar Disorder

Pao Huan Chen, Cheng Yi Hsiao, Shuo Ju Chiang, Shang Ying Tsai

Research output: Contribution to journal › Letter › peer-review

1 Citation (Scopus)

Abstract

Existing data indicate that lithium treatment may reduce the risk of cardiovascular diseases in patients with bipolar disorder (BD).1-3 Our recent pilot study demonstrated that longer lithium exposure was associated with favorable diastolic function among patients with BD.4 The findings suggest that lithium treatment may help prevent heart failure in individuals with BD. However, few studies so far have investigated the association between lithium treatment and cardiac structure in patients with BD. Among the geometric patterns of myocardium, left ventricular (LV) concentric remodeling and LV concentric hypertrophy are characterized by increased wall thickness and are jointly referred to as LV concentricity.5 Substantial evidence has indicated that LV concentricity is a critical risk marker of heart failure.5 The current study aimed to evaluate whether lithium treatment was associated with favorable LV geometric patterns among patients with BD.

Original language	English
Pages (from-to)	59-61
Number of pages	3
Journal	Psychiatry and Clinical Neurosciences
Volume	77
Issue number	1
DOIs	https://doi.org/10.1111/pcn.13497
Publication status	Published - Jan 2023

ASJC Scopus subject areas

General Neuroscience
Neurology
Clinical Neurology
Psychiatry and Mental health

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1111/pcn.13497

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@article{d5243a0df0944c51b109ec626edbca99,

title = "Association of Lithium Treatment With Reduced Left Ventricular Concentricity in Patients With Bipolar Disorder",

abstract = "Existing data indicate that lithium treatment may reduce the risk of cardiovascular diseases in patients with bipolar disorder (BD).1-3 Our recent pilot study demonstrated that longer lithium exposure was associated with favorable diastolic function among patients with BD.4 The findings suggest that lithium treatment may help prevent heart failure in individuals with BD. However, few studies so far have investigated the association between lithium treatment and cardiac structure in patients with BD. Among the geometric patterns of myocardium, left ventricular (LV) concentric remodeling and LV concentric hypertrophy are characterized by increased wall thickness and are jointly referred to as LV concentricity.5 Substantial evidence has indicated that LV concentricity is a critical risk marker of heart failure.5 The current study aimed to evaluate whether lithium treatment was associated with favorable LV geometric patterns among patients with BD.",

author = "Chen, {Pao Huan} and Hsiao, {Cheng Yi} and Chiang, {Shuo Ju} and Tsai, {Shang Ying}",

note = "Funding Information: The present study was supported by research grants from the Ministry of Science and Technology (MOST 106–2314–B–038–050–MY3) and the Higher Education Sprout Project by the Ministry of Education (DP2–110–21121–01–I–02) in Taiwan. ",

year = "2023",

month = jan,

doi = "10.1111/pcn.13497",

language = "English",

volume = "77",

pages = "59--61",

journal = "Psychiatry and Clinical Neurosciences",

issn = "1323-1316",

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T1 - Association of Lithium Treatment With Reduced Left Ventricular Concentricity in Patients With Bipolar Disorder

AU - Chen, Pao Huan

AU - Hsiao, Cheng Yi

AU - Chiang, Shuo Ju

AU - Tsai, Shang Ying

N1 - Funding Information: The present study was supported by research grants from the Ministry of Science and Technology (MOST 106–2314–B–038–050–MY3) and the Higher Education Sprout Project by the Ministry of Education (DP2–110–21121–01–I–02) in Taiwan.

PY - 2023/1

Y1 - 2023/1

N2 - Existing data indicate that lithium treatment may reduce the risk of cardiovascular diseases in patients with bipolar disorder (BD).1-3 Our recent pilot study demonstrated that longer lithium exposure was associated with favorable diastolic function among patients with BD.4 The findings suggest that lithium treatment may help prevent heart failure in individuals with BD. However, few studies so far have investigated the association between lithium treatment and cardiac structure in patients with BD. Among the geometric patterns of myocardium, left ventricular (LV) concentric remodeling and LV concentric hypertrophy are characterized by increased wall thickness and are jointly referred to as LV concentricity.5 Substantial evidence has indicated that LV concentricity is a critical risk marker of heart failure.5 The current study aimed to evaluate whether lithium treatment was associated with favorable LV geometric patterns among patients with BD.

AB - Existing data indicate that lithium treatment may reduce the risk of cardiovascular diseases in patients with bipolar disorder (BD).1-3 Our recent pilot study demonstrated that longer lithium exposure was associated with favorable diastolic function among patients with BD.4 The findings suggest that lithium treatment may help prevent heart failure in individuals with BD. However, few studies so far have investigated the association between lithium treatment and cardiac structure in patients with BD. Among the geometric patterns of myocardium, left ventricular (LV) concentric remodeling and LV concentric hypertrophy are characterized by increased wall thickness and are jointly referred to as LV concentricity.5 Substantial evidence has indicated that LV concentricity is a critical risk marker of heart failure.5 The current study aimed to evaluate whether lithium treatment was associated with favorable LV geometric patterns among patients with BD.

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Association of Lithium Treatment With Reduced Left Ventricular Concentricity in Patients With Bipolar Disorder

Abstract

ASJC Scopus subject areas

UN SDGs

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