Association of cataract with chronic rhinosinusitis: A population-based case-control study

Purpose: To assess the association between cataract and chronic rhinosinusitis (CRS) using a population-based database. Methods: The study sample for this case-control study was retrieved from Taiwan's Longitudinal Health Insurance Database 2000. The study included 3045 patients who had undergone cataract surgery as cases and 9135 subjects without cataract as controls. Conditional logistic regression was performed to calculate odds ratios (ORs) and corresponding 95% confidence intervals (CIs) of having a prior diagnosis of CRS in cases versus controls. Results: In the total study sample, the prevalence of prior CRS was 3.88%; 5.16% among cases and 3.45% among controls (p69 years). It is particularly noteworthy that younger groups demonstrated higher ORs for prior CRS among cases compared to controls. In particular, the adjusted OR for cases aged 40-50 years was 1.71 (95% CI 1.09∼2.66; p