Abstract
We studied the apoliprotein E (apo-E) allele frequencies and intronic polymorphism of the presenilin-1 (PS-1) gene in 55 patients with late-onset Alzheimer's disease (AD) and 93 age- and sex-matched controls. The apoE ε4 allele frequency was significantly higher in the AD group than in the control group (0.255 versus 0.070, P
Original language | English |
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Pages (from-to) | 158-161 |
Number of pages | 4 |
Journal | Journal of the Neurological Sciences |
Volume | 157 |
Issue number | 2 |
DOIs | |
Publication status | Published - May 7 1998 |
Externally published | Yes |
Keywords
- Alzheimer's disease
- Apolipoprotein E
- Chinese
- Dementia
- Genetics
- Presenilin- 1
ASJC Scopus subject areas
- Ageing
- Clinical Neurology
- Surgery
- Neuroscience(all)
- Developmental Neuroscience
- Neurology