Anxiety disorder (AD) is commonly associated with a number of physical illnesses. No previous study has investigated the association between AD and sudden sensorineural hearing loss (SSNHL). In this study, we investigated the association between prior AD and SSNHL using a population-based dataset in Taiwan. Sampled subjects of this case–control study were retrieved from the Taiwan “Longitudinal Health Insurance Database”. We identified 3,522 patients who had a diagnosis of SSNHL as cases and 10,566 age- and gender-matched subjects without SSNHL as controls. A conditional logistic regression was used to calculate the odds ratio (OR) for having previously been diagnosed with AD between cases and controls. We found that of 14,088 patients, 13.4 % had a prior AD diagnosis, 17.8 and 11.9 % for the SSNHL group and controls, respectively. After adjusting for patient socioeconomic characteristics and comorbid medical disorders, SSNHL patients were more likely to have prior AD than the controls (OR 1.49, 95 % confidence interval (CI) 1.34–1.66, p 

Original languageEnglish
Pages (from-to)2673-2678
Number of pages6
JournalEuropean Archives of Oto-Rhino-Laryngology
Issue number10
Publication statusPublished - Oct 24 2015


  • Anxiety disorder
  • Sudden sensorineural hearing loss

ASJC Scopus subject areas

  • Otorhinolaryngology


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