Abstract
The association between sex, nutritional status, and the severity of dengue hemorrhagic fever/dengue shock syndrome (DHF/DSS), and immune status was investigated in 245 Vietnamese infants with predominantly primary infections with dengue virus. Male and female infants were at equal risk of developing DHF/DSS. However, infants of low height and weight for age were under-represented among DHF/DSS cases compared with 533 healthy baby clinic infant controls. Acute illness phase blood levels of selected cytokines (interferon-γ and tumor necrosis factor-α) and serum levels of antibodies to dengue virus were elevated in the same range in male and female infants with DHF/DSS, as well as in infants with and without malnutrition.
Original language | English |
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Pages (from-to) | 370-374 |
Number of pages | 5 |
Journal | American Journal of Tropical Medicine and Hygiene |
Volume | 72 |
Issue number | 4 |
DOIs | |
Publication status | Published - Apr 2005 |
Externally published | Yes |
ASJC Scopus subject areas
- Infectious Diseases
- Virology
- Parasitology