TY - JOUR
T1 - Association between neovascular age-related macular degeneration and dementia
T2 - A population-based case-control study in Taiwan
AU - Chung, Shiu Dong
AU - Lee, Cha Ze
AU - Kao, Li Ting
AU - Lin, Herng Ching
AU - Tsai, Ming Chieh
AU - Sheu, Jau Jiuan
PY - 2015/3/6
Y1 - 2015/3/6
N2 - Most available studies focusing on the association between neovascular age-related macular degeneration (AMD) and dementia have conflicting results. This study aimed to investigate the association between previously diagnosed AMD and dementia using a populationbased dataset in Taiwan. Methods Data for this case-control study were retrospectively collected from the Taiwan National Health Insurance Research Database. We identified 13,402 subjects who had a diagnosis of dementia as cases, and 40,206 subjects without dementia as controls. A conditional logistic regression was used to examine the association of dementia with previously diagnosed neovascular AMD. Results We found that of the study sample of 53,608 subjects, 1.01% had previously diagnosed neovascular AMD, 1.35%and 0.90% for cases and the controls, respectively (p
AB - Most available studies focusing on the association between neovascular age-related macular degeneration (AMD) and dementia have conflicting results. This study aimed to investigate the association between previously diagnosed AMD and dementia using a populationbased dataset in Taiwan. Methods Data for this case-control study were retrospectively collected from the Taiwan National Health Insurance Research Database. We identified 13,402 subjects who had a diagnosis of dementia as cases, and 40,206 subjects without dementia as controls. A conditional logistic regression was used to examine the association of dementia with previously diagnosed neovascular AMD. Results We found that of the study sample of 53,608 subjects, 1.01% had previously diagnosed neovascular AMD, 1.35%and 0.90% for cases and the controls, respectively (p
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U2 - 10.1371/journal.pone.0120003
DO - 10.1371/journal.pone.0120003
M3 - Article
C2 - 25748702
AN - SCOPUS:84924207417
SN - 1932-6203
VL - 10
JO - PLoS One
JF - PLoS One
IS - 3
M1 - e0120003
ER -