Association between multiple sclerosis and chronic periodontitis: A population-based pilot study

J. J. Sheu; H. C. Lin

doi:10.1111/ene.12103

Association between multiple sclerosis and chronic periodontitis: A population-based pilot study

J. J. Sheu, H. C. Lin

Research output: Contribution to journal › Article › peer-review

38 Citations (Scopus)

Abstract

Background and purpose: The pathogenesis of multiple sclerosis (MS) is still not fully understood, but multiple infections are known to be crucial in the development of the disease. Periodontitis caused by periodontopathic polymicrobial infections is among the most common chronic infectious disorders. This case-control study aimed to investigate the association between chronic periodontitis (CP) and MS using a population-based dataset in Taiwan. Methods: This study included 316 cases who had a diagnosis of MS and 1580 randomly selected controls. We performed conditional logistic regressions to investigate the association between MS and having been previously diagnosed with CP. Results: The results reveal that the prevalence of earlier CP was 25.6% and 15.4% for cases and controls, respectively (P

Original language	English
Pages (from-to)	1053-1059
Number of pages	7
Journal	European Journal of Neurology
Volume	20
Issue number	7
DOIs	https://doi.org/10.1111/ene.12103
Publication status	Published - Jul 2013

Keywords

Chronic periodontitis
Multiple sclerosis
Periodontitis

ASJC Scopus subject areas

Clinical Neurology
Neurology

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10.1111/ene.12103

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abstract = "Background and purpose: The pathogenesis of multiple sclerosis (MS) is still not fully understood, but multiple infections are known to be crucial in the development of the disease. Periodontitis caused by periodontopathic polymicrobial infections is among the most common chronic infectious disorders. This case-control study aimed to investigate the association between chronic periodontitis (CP) and MS using a population-based dataset in Taiwan. Methods: This study included 316 cases who had a diagnosis of MS and 1580 randomly selected controls. We performed conditional logistic regressions to investigate the association between MS and having been previously diagnosed with CP. Results: The results reveal that the prevalence of earlier CP was 25.6% and 15.4% for cases and controls, respectively (P",

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AB - Background and purpose: The pathogenesis of multiple sclerosis (MS) is still not fully understood, but multiple infections are known to be crucial in the development of the disease. Periodontitis caused by periodontopathic polymicrobial infections is among the most common chronic infectious disorders. This case-control study aimed to investigate the association between chronic periodontitis (CP) and MS using a population-based dataset in Taiwan. Methods: This study included 316 cases who had a diagnosis of MS and 1580 randomly selected controls. We performed conditional logistic regressions to investigate the association between MS and having been previously diagnosed with CP. Results: The results reveal that the prevalence of earlier CP was 25.6% and 15.4% for cases and controls, respectively (P

KW - Chronic periodontitis

KW - Multiple sclerosis

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Association between multiple sclerosis and chronic periodontitis: A population-based pilot study

Abstract

Keywords

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