Abstract
Neurotransmitter dopamine has relation with neuro-psychiatric disease, it also has effect on motor function for healthy individuals and also determines the outcome of rehabilitation for neuro-psychiatric disease patients. Finger Tapping Test (FTT), a neuro-psychological test, is thought to be associated with dopamine. Therefore, the goal of this study is to investigate the association relationship between dopamine genes polymorphism (DRD2 TaqI) and FTT. Method: We recruit healthy Han Chinese, age between 20 and 60 years old, having no neuro-psychiatric illness and family history for dopamine genes polymorphism (DRD2 TaqI) and FTT assessment. Result: Total 106 cases were enrolled in the study. Analysis the relationship between FTT and DRD2 gene polymorphism showed that A1/A2 genotype has higher score of finger tapping test than A1/A1 or A2/A2 genotype (p=0.031). Conclusion: Our results show that there is significant relationship between FTT and DRD2 gene polymorphism.
| Translated title of the contribution | Associated study between Dopamine DRD2 gene polymorphism and finger tapping test |
|---|---|
| Original language | Chinese (Traditional) |
| Pages (from-to) | 245-250 |
| Number of pages | 6 |
| Journal | 台灣復健醫學雜誌 |
| Volume | 37 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Dec 2009 |