Aspergillus coinfection in critically Ill patients with severe dengue

Yang Han Lin; Ting Chia Chang; Wen Liang Yu; Willy Chou; Chin Ming Chen

doi:10.1016/j.jiph.2023.09.008

Aspergillus coinfection in critically Ill patients with severe dengue

Yang Han Lin, Ting Chia Chang, Wen Liang Yu, Willy Chou, Chin Ming Chen

Research output: Contribution to journal › Article › peer-review

Abstract

In 2014–2015, a significant outbreak of dengue fever occurred in southern Taiwan, with a subsequent decline in dengue incidence. Despite this, there is emerging concern about virus-associated aspergillosis, yet limited research has explored coinfections involving dengue and aspergillosis. We conducted a retrospective study at a single center in Southern Taiwan, specifically focusing on dengue patients admitted to the intensive care unit during the period between July and November 2015. Among the 142 dengue patients studied, only 8.06 % (10/142) underwent serum galactomannan testing, with a single patient undergoing bronchoalveolar lavage (BAL) galactomannan assay. Out of those tested, 20 % (2/10) returned positive serum galactomannan results. Herein, we present two consecutive cases of coinfection involving dengue and pulmonary aspergillosis in immunocompetent patients.

Original language	English
Pages (from-to)	1893-1897
Number of pages	5
Journal	Journal of Infection and Public Health
Volume	16
Issue number	12
DOIs	https://doi.org/10.1016/j.jiph.2023.09.008
Publication status	Published - Dec 2023

Keywords

Aspergillus
Coinfection
Dengue
Virus-associated fungal disease

ASJC Scopus subject areas

Public Health, Environmental and Occupational Health
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.jiph.2023.09.008

Cite this

@article{2724b7fb3e074c929ea2513fb6b5e832,

title = "Aspergillus coinfection in critically Ill patients with severe dengue",

abstract = "In 2014–2015, a significant outbreak of dengue fever occurred in southern Taiwan, with a subsequent decline in dengue incidence. Despite this, there is emerging concern about virus-associated aspergillosis, yet limited research has explored coinfections involving dengue and aspergillosis. We conducted a retrospective study at a single center in Southern Taiwan, specifically focusing on dengue patients admitted to the intensive care unit during the period between July and November 2015. Among the 142 dengue patients studied, only 8.06 % (10/142) underwent serum galactomannan testing, with a single patient undergoing bronchoalveolar lavage (BAL) galactomannan assay. Out of those tested, 20 % (2/10) returned positive serum galactomannan results. Herein, we present two consecutive cases of coinfection involving dengue and pulmonary aspergillosis in immunocompetent patients.",

keywords = "Aspergillus, Coinfection, Dengue, Virus-associated fungal disease",

author = "Lin, {Yang Han} and Chang, {Ting Chia} and Yu, {Wen Liang} and Willy Chou and Chen, {Chin Ming}",

note = "Publisher Copyright: {\textcopyright} 2023 The Author(s)",

year = "2023",

month = dec,

doi = "10.1016/j.jiph.2023.09.008",

language = "English",

volume = "16",

pages = "1893--1897",

journal = "Journal of Infection and Public Health",

issn = "1876-0341",

publisher = "Elsevier BV",

number = "12",

}

TY - JOUR

T1 - Aspergillus coinfection in critically Ill patients with severe dengue

AU - Lin, Yang Han

AU - Chang, Ting Chia

AU - Yu, Wen Liang

AU - Chou, Willy

AU - Chen, Chin Ming

PY - 2023/12

Y1 - 2023/12

N2 - In 2014–2015, a significant outbreak of dengue fever occurred in southern Taiwan, with a subsequent decline in dengue incidence. Despite this, there is emerging concern about virus-associated aspergillosis, yet limited research has explored coinfections involving dengue and aspergillosis. We conducted a retrospective study at a single center in Southern Taiwan, specifically focusing on dengue patients admitted to the intensive care unit during the period between July and November 2015. Among the 142 dengue patients studied, only 8.06 % (10/142) underwent serum galactomannan testing, with a single patient undergoing bronchoalveolar lavage (BAL) galactomannan assay. Out of those tested, 20 % (2/10) returned positive serum galactomannan results. Herein, we present two consecutive cases of coinfection involving dengue and pulmonary aspergillosis in immunocompetent patients.

AB - In 2014–2015, a significant outbreak of dengue fever occurred in southern Taiwan, with a subsequent decline in dengue incidence. Despite this, there is emerging concern about virus-associated aspergillosis, yet limited research has explored coinfections involving dengue and aspergillosis. We conducted a retrospective study at a single center in Southern Taiwan, specifically focusing on dengue patients admitted to the intensive care unit during the period between July and November 2015. Among the 142 dengue patients studied, only 8.06 % (10/142) underwent serum galactomannan testing, with a single patient undergoing bronchoalveolar lavage (BAL) galactomannan assay. Out of those tested, 20 % (2/10) returned positive serum galactomannan results. Herein, we present two consecutive cases of coinfection involving dengue and pulmonary aspergillosis in immunocompetent patients.

KW - Aspergillus

KW - Coinfection

KW - Dengue

KW - Virus-associated fungal disease

UR - http://www.scopus.com/inward/record.url?scp=85174726838&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85174726838&partnerID=8YFLogxK

U2 - 10.1016/j.jiph.2023.09.008

DO - 10.1016/j.jiph.2023.09.008

M3 - Article

C2 - 37866267

AN - SCOPUS:85174726838

SN - 1876-0341

VL - 16

SP - 1893

EP - 1897

JO - Journal of Infection and Public Health

JF - Journal of Infection and Public Health

IS - 12

ER -

Aspergillus coinfection in critically Ill patients with severe dengue

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this