Aqueous extract of Solanum nigrum attenuates Angiotensin-II induced cardiac hypertrophy and improves cardiac function by repressing protein kinase C-ζ to restore HSF2 deSUMOlyation and Mel-18-IGF-IIR signaling suppression

Hung Jen Lin, Ramasamy Mahendran, Hsiang Yen Huang, Ping Ling Chiu, Yung Ming Chang, Cecilia Hsuan Day, Ray Jade Chen, V. Vijaya Padma, Yang Liang-Yo, Wei Wen Kuo, Chih Yang Huang

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Pharmacology, Toxicology and Pharmaceutical Science